Structure analysis

Crystal structure of dihydroneopterin aldolase from Bacillus anthracis complex with 9-METHYLGUANINE

X-ray diffraction
2Å resolution
Source organism: Bacillus cereus BAG3X2-1
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer
Accessible surface area: 21366.31 Å2
Buried surface area: 9922.6 Å2
Dissociation area: 4,390.91 Å2
Dissociation energy (ΔGdiss): 31.29 kcal/mol
Dissociation entropy (TΔSdiss): 36.88 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-165646
Assembly 2
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Multimeric state: homo tetramer
Accessible surface area: 21581.93 Å2
Buried surface area: 9820.2 Å2
Dissociation area: 4,408.51 Å2
Dissociation energy (ΔGdiss): 30.99 kcal/mol
Dissociation entropy (TΔSdiss): 36.9 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-165646

Macromolecules

Chains: A, B, C, D, E, F, G, H
Length: 123 amino acids
Theoretical weight: 14.36 KDa
Source organism: Bacillus cereus BAG3X2-1
Expression system: Escherichia coli BL21(DE3)
InterPro:
CATH: GTP Cyclohydrolase I, domain 2

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