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Crystal structure of Trypanosoma brucei macrodomain in complex with ADP-ribose

X-ray diffraction
1.7Å resolution
PDB entry 5fsy coloured by chain, front view.
PDB entry 5fsy coloured by chain, side view.
PDB entry 5fsy coloured by chain, top view.
Source organism: Trypanosoma brucei
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Macro domain-containing protein
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Multimeric state: monomeric
Accessible surface area: 10451.01 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-111900

Macromolecules

Macro domain-containing protein
Chain: A
Length: 266 amino acids
Theoretical weight: 29.18 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C9ZP98 (Residues: 1-265; Coverage: 100%)
Gene name: TbgDal_V3640
Pfam: Macro domain
InterPro:
CATH: Leucine Aminopeptidase, subunit E, domain 1
Macro domain-containing protein in PDB entry 5fsy, assembly 1, front view.
Macro domain-containing protein in PDB entry 5fsy, assembly 1, side view.
Macro domain-containing protein in PDB entry 5fsy, assembly 1, top view.
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