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Crystal Structure of BAF47 and BAF155 Complex

X-ray diffraction
2.052Å resolution
PDB entry 5gjk coloured by chain, front view.
PDB entry 5gjk coloured by chain, side view.
PDB entry 5gjk coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: SWI/SNF complex subunit SMARCC1 and SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
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Multimeric state: hetero tetramer
Accessible surface area: 16149.46 Å2
Buried surface area: 5597.78 Å2
Dissociation area: 780.83 Å2
Dissociation energy (ΔGdiss): -1.09 kcal/mol
Dissociation entropy (TΔSdiss): 12.31 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-171404

Macromolecules

SWI/SNF complex subunit SMARCC1
Chain: A
Length: 94 amino acids
Theoretical weight: 11.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q92922 (Residues: 447-540; Coverage: 9%)
Gene names: BAF155, SMARCC1
Pfam: SWIRM domain
InterPro:
CATH: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
SWI/SNF complex subunit SMARCC1 in PDB entry 5gjk, assembly 1, front view.
SWI/SNF complex subunit SMARCC1 in PDB entry 5gjk, assembly 1, side view.
SWI/SNF complex subunit SMARCC1 in PDB entry 5gjk, assembly 1, top view.
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SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Chain: B
Length: 68 amino acids
Theoretical weight: 7.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12824 (Residues: 183-249; Coverage: 17%)
Gene names: BAF47, INI1, SMARCB1, SNF5L1
Pfam: SNF5 / SMARCB1 / INI1
InterPro: SNF5/SMARCB1/INI1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 in PDB entry 5gjk, assembly 1, front view.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 in PDB entry 5gjk, assembly 1, side view.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 in PDB entry 5gjk, assembly 1, top view.
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