› › Structure analysis

Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 19a

X-ray diffraction
1.7Å resolution
PDB entry 5ibf coloured by chain, front view.
PDB entry 5ibf coloured by chain, side view.
PDB entry 5ibf coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Mycocyclosin synthase
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 16466.25 Å2
Buried surface area: 1541.04 Å2
Dissociation area: 125.16 Å2
Dissociation energy (ΔGdiss): 21.97 kcal/mol
Dissociation entropy (TΔSdiss): 0.6 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-162003

Macromolecules

Mycocyclosin synthase
Chain: A
Length: 396 amino acids
Theoretical weight: 43.31 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPP7 (Residues: 1-396; Coverage: 100%)
Gene names: MTCY339.34c, Rv2276, cyp121
Pfam: Cytochrome P450
InterPro:
CATH: Cytochrome P450
Mycocyclosin synthase in PDB entry 5ibf, assembly 1, front view.
Mycocyclosin synthase in PDB entry 5ibf, assembly 1, side view.
Mycocyclosin synthase in PDB entry 5ibf, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links