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Crystal structure of anthranilate synthase component I from Streptococcus pneumoniae TIGR4

X-ray diffraction
2.2Å resolution
PDB entry 5kck coloured by chain, front view.
PDB entry 5kck coloured by chain, side view.
PDB entry 5kck coloured by chain, top view.
Source organism: Streptococcus pneumoniae TIGR4
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Anthranilate synthase component 1
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Multimeric state: homo dimer
Accessible surface area: 37006.35 Å2
Buried surface area: 10501.46 Å2
Dissociation area: 4,744.85 Å2
Dissociation energy (ΔGdiss): 74.19 kcal/mol
Dissociation entropy (TΔSdiss): 15.26 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-101478

Macromolecules

Anthranilate synthase component 1
Chain: A
Length: 450 amino acids
Theoretical weight: 51.52 KDa
Source organism: Streptococcus pneumoniae TIGR4
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: A0A0H2URN1 (Residues: 2-448; Coverage: 99%)
Gene names: SP_1817, trpE
Pfam:
InterPro:
CATH: Anthranilate synthase
Anthranilate synthase component 1 in PDB entry 5kck, assembly 1, front view.
Anthranilate synthase component 1 in PDB entry 5kck, assembly 1, side view.
Anthranilate synthase component 1 in PDB entry 5kck, assembly 1, top view.
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