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The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=-6

Electron Microscopy
8.4Å resolution
PDB entry 5mdb coloured by chain, front view.
PDB entry 5mdb coloured by chain, side view.
PDB entry 5mdb coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Assembly composition:
hetero tetradecamer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Gag Polyprotein
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Multimeric state: hetero tetradecamer
PDBe Complex ID: PDB-CPX-180776

Macromolecules

Gag protein
Chains: A, B, C, D, E, F, G, W
Length: 74 amino acids
Theoretical weight: 8.37 KDa
Source organism: Human immunodeficiency virus 1
UniProt:
  • Canonical: Q72497 (Residues: 280-353; Coverage: 15%)
Gene name: gag
Pfam: Gag protein p24 C-terminal domain
InterPro:
Gag protein in PDB entry 5mdb, assembly 1, front view.
Gag protein in PDB entry 5mdb, assembly 1, side view.
Gag protein in PDB entry 5mdb, assembly 1, top view.
Molecule details ›

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Gag protein
Chains: H, I, J, a, b, f
Length: 147 amino acids
Theoretical weight: 16.3 KDa
Source organism: Human immunodeficiency virus 1
UniProt:
  • Canonical: Q72497 (Residues: 133-279; Coverage: 29%)
Gene name: gag
Pfam: gag protein p24 N-terminal domain
InterPro:
Gag protein in PDB entry 5mdb, assembly 1, front view.
Gag protein in PDB entry 5mdb, assembly 1, side view.
Gag protein in PDB entry 5mdb, assembly 1, top view.
Molecule details ›

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