Molecular basis of human kinesin-8 function and inhibition
Source organisms:
Biochemical function:
metal ion binding
Biological process: microtubule-based process
Cellular component: microtubule
Biological process: microtubule-based process
Cellular component: microtubule
Protein families (Pfam)![The deposited structure of PDB entry 5ogc contains 1 copy of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin alpha-1B chain. Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/5ogc_2_A_Pfam_PF03953_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5ogc</span> contains 1 copy of Pfam domain <span class='highlight'>PF03953 (Tubulin C-terminal domain)</span> in <span class='highlight'>Tubulin alpha-1B chain</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")
![The deposited structure of PDB entry 5ogc contains 1 copy of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin beta chain. Showing 1 copy in chain C [auth B].](https://www.ebi.ac.uk/pdbe/static/entry/5ogc_3_B_Pfam_PF03953_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5ogc</span> contains 1 copy of Pfam domain <span class='highlight'>PF03953 (Tubulin C-terminal domain)</span> in <span class='highlight'>Tubulin beta chain</span>. Showing 1 copy in chain <span class='highlight'>C [auth B]</span>.")
![The deposited structure of PDB entry 5ogc contains 1 copy of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin alpha-1B chain. Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/5ogc_2_A_Pfam_PF00091_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5ogc</span> contains 1 copy of Pfam domain <span class='highlight'>PF00091 (Tubulin/FtsZ family, GTPase domain)</span> in <span class='highlight'>Tubulin alpha-1B chain</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")
![The deposited structure of PDB entry 5ogc contains 1 copy of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin beta chain. Showing 1 copy in chain C [auth B].](https://www.ebi.ac.uk/pdbe/static/entry/5ogc_3_B_Pfam_PF00091_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5ogc</span> contains 1 copy of Pfam domain <span class='highlight'>PF00091 (Tubulin/FtsZ family, GTPase domain)</span> in <span class='highlight'>Tubulin beta chain</span>. Showing 1 copy in chain <span class='highlight'>C [auth B]</span>.")
![The deposited structure of PDB entry 5ogc contains 1 copy of Pfam domain PF00225 (Kinesin motor domain) in Kinesin-like protein KIF18A. Showing 1 copy in chain A [auth K].](https://www.ebi.ac.uk/pdbe/static/entry/5ogc_1_K_Pfam_PF00225_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5ogc</span> contains 1 copy of Pfam domain <span class='highlight'>PF00225 (Kinesin motor domain)</span> in <span class='highlight'>Kinesin-like protein KIF18A</span>. Showing 1 copy in chain <span class='highlight'>A [auth K]</span>.")
InterPro annotations