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The crystal structure of CK2alpha in complex with an analogue of compound 22

X-ray diffraction
1.9Å resolution
PDB entry 5ots coloured by chain, front view.
PDB entry 5ots coloured by chain, side view.
PDB entry 5ots coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Casein kinase II subunit alpha
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Multimeric state: monomeric
Accessible surface area: 15586.12 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-159383

Macromolecules

Casein kinase II subunit alpha
Chain: A
Length: 342 amino acids
Theoretical weight: 40.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P68400 (Residues: 2-329; Coverage: 84%)
  • Best match: P68400-2 (Residues: 1-193)
Gene names: CK2A1, CSNK2A1
Pfam: Protein kinase domain
InterPro:
CATH:
Casein kinase II subunit alpha in PDB entry 5ots, assembly 1, front view.
Casein kinase II subunit alpha in PDB entry 5ots, assembly 1, side view.
Casein kinase II subunit alpha in PDB entry 5ots, assembly 1, top view.
PDBe-KB: UniProt Coverage View: P68400  
134250100150200250300
 
100200300
UniProt
P68400
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