› › Structure analysis

PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000487a

X-ray diffraction
1.613Å resolution
PDB entry 5qfu coloured by chain, front view.
PDB entry 5qfu coloured by chain, side view.
PDB entry 5qfu coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Tyrosine-protein phosphatase non-receptor type 1
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13752.42 Å2
Buried surface area: 130.42 Å2
Dissociation area: 65.21 Å2
Dissociation energy (ΔGdiss): -2.79 kcal/mol
Dissociation entropy (TΔSdiss): 1.68 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148259

Macromolecules

Tyrosine-protein phosphatase non-receptor type 1
Chain: A
Length: 321 amino acids
Theoretical weight: 37.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P18031 (Residues: 1-321; Coverage: 74%)
Gene names: PTP1B, PTPN1
Pfam: Protein-tyrosine phosphatase
InterPro:
CATH: Protein tyrosine phosphatase superfamily
Tyrosine-protein phosphatase non-receptor type 1 in PDB entry 5qfu, assembly 1, front view.
Tyrosine-protein phosphatase non-receptor type 1 in PDB entry 5qfu, assembly 1, side view.
Tyrosine-protein phosphatase non-receptor type 1 in PDB entry 5qfu, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links