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Tubulin-Z48847594-complex

X-ray diffraction
2.3Å resolution
PDB entry 5s4o coloured by chain, front view.
PDB entry 5s4o coloured by chain, side view.
PDB entry 5s4o coloured by chain, top view.
Source organisms:
Assembly composition:
hetero hexamer (preferred)
Entry contents: 4 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero hexamer
Accessible surface area: 80436.8 Å2
Buried surface area: 23053.05 Å2
Dissociation area: 1,209.14 Å2
Dissociation energy (ΔGdiss): -6.6 kcal/mol
Dissociation entropy (TΔSdiss): 14.78 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-237085

Macromolecules

Tubulin alpha-1B chain
Chains: A, C
Length: 451 amino acids
Theoretical weight: 50.2 KDa
Source organism: Bos taurus
Tubulin alpha-1B chain in PDB entry 5s4o, assembly 1, front view.
Tubulin alpha-1B chain in PDB entry 5s4o, assembly 1, side view.
Tubulin alpha-1B chain in PDB entry 5s4o, assembly 1, top view.
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Tubulin beta-2B chain
Chains: B, D
Length: 445 amino acids
Theoretical weight: 50 KDa
Source organism: Bos taurus
Tubulin beta-2B chain in PDB entry 5s4o, assembly 1, front view.
Tubulin beta-2B chain in PDB entry 5s4o, assembly 1, side view.
Tubulin beta-2B chain in PDB entry 5s4o, assembly 1, top view.
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Stathmin-4
Chain: E
Length: 143 amino acids
Theoretical weight: 16.84 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
Stathmin-4 in PDB entry 5s4o, assembly 1, front view.
Stathmin-4 in PDB entry 5s4o, assembly 1, side view.
Stathmin-4 in PDB entry 5s4o, assembly 1, top view.
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Tubulin-Tyrosine Ligase
Chain: F
Length: 384 amino acids
Theoretical weight: 44.38 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
Tubulin-Tyrosine Ligase in PDB entry 5s4o, assembly 1, front view.
Tubulin-Tyrosine Ligase in PDB entry 5s4o, assembly 1, side view.
Tubulin-Tyrosine Ligase in PDB entry 5s4o, assembly 1, top view.
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