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Structure of the STRA6 receptor for retinol uptake in complex with calmodulin

Electron Microscopy
3.9Å resolution
PDB entry 5sy1 coloured by chain, front view.
PDB entry 5sy1 coloured by chain, side view.
PDB entry 5sy1 coloured by chain, top view.
Source organisms:
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Receptor for retinol uptake stra6 and EF-hand domain-containing protein
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Multimeric state: hetero tetramer
Accessible surface area: 73608.32 Å2
Buried surface area: 25855.52 Å2
Dissociation area: 6,817.1 Å2
Dissociation energy (ΔGdiss): 84.71 kcal/mol
Dissociation entropy (TΔSdiss): 27.45 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-103324

Macromolecules

EF-hand domain-containing protein
Chains: C, D
Length: 149 amino acids
Theoretical weight: 16.83 KDa
Source organism: Spodoptera frugiperda
UniProt:
  • Canonical: A0A1C7D1B9 (Residues: 1-149; Coverage: 100%)
Gene name: LOC118276129
Pfam: EF-hand domain pair
InterPro:
EF-hand domain-containing protein in PDB entry 5sy1, assembly 1, front view.
EF-hand domain-containing protein in PDB entry 5sy1, assembly 1, side view.
EF-hand domain-containing protein in PDB entry 5sy1, assembly 1, top view.
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Receptor for retinol uptake stra6
Chains: A, B
Length: 670 amino acids
Theoretical weight: 75.55 KDa
Source organism: Danio rerio
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: F1RAX4 (Residues: 1-670; Coverage: 100%)
Gene name: stra6
Pfam: Retinol binding protein receptor
InterPro: Receptor for retinol uptake STRA6-like
Receptor for retinol uptake stra6 in PDB entry 5sy1, assembly 1, front view.
Receptor for retinol uptake stra6 in PDB entry 5sy1, assembly 1, side view.
Receptor for retinol uptake stra6 in PDB entry 5sy1, assembly 1, top view.
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