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Crystal structure of 354BG18 Fab

X-ray diffraction
1.3Å resolution
PDB entry 5ud9 coloured by chain, front view.
PDB entry 5ud9 coloured by chain, side view.
PDB entry 5ud9 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-heavy chain and IG-light lambda chain
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Multimeric state: hetero dimer
Accessible surface area: 19530.34 Å2
Buried surface area: 3349.23 Å2
Dissociation area: 1,674.62 Å2
Dissociation energy (ΔGdiss): 18.1 kcal/mol
Dissociation entropy (TΔSdiss): 13.14 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-231442

Macromolecules

Fab heavy chain
Chain: H
Length: 241 amino acids
Theoretical weight: 26.16 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
InterPro:
CATH: Immunoglobulins
Fab heavy chain in PDB entry 5ud9, assembly 1, front view.
Fab heavy chain in PDB entry 5ud9, assembly 1, side view.
Fab heavy chain in PDB entry 5ud9, assembly 1, top view.
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Light chain
Chain: L
Length: 215 amino acids
Theoretical weight: 23.02 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
InterPro:
CATH: Immunoglobulins
Light chain in PDB entry 5ud9, assembly 1, front view.
Light chain in PDB entry 5ud9, assembly 1, side view.
Light chain in PDB entry 5ud9, assembly 1, top view.
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