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Clostridium difficile Toxin B (TcdB) glucosyltransferase domain co-crystallized with apigenin

Source organism: Clostridioides difficile
Biochemical function: glycosyltransferase activity
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF12919
Domain description: TcdA/TcdB catalytic glycosyltransferase domain
Occurring in:
  1. Glucosyltransferase TcdB
The deposited structure of PDB entry 5uqt contains 2 copies of Pfam domain PF12919 (TcdA/TcdB catalytic glycosyltransferase domain) in Glucosyltransferase TcdB. Showing 1 copy in chain A.

PF12918
Domain description: TcdB toxin N-terminal helical domain
Occurring in:
  1. Glucosyltransferase TcdB
The deposited structure of PDB entry 5uqt contains 2 copies of Pfam domain PF12918 (TcdB toxin N-terminal helical domain) in Glucosyltransferase TcdB. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR024770
Domain description: TcdA/TcdB toxin, catalytic glycosyltransferase domain
Occurring in:
  1. Glucosyltransferase TcdB
IPR024772
Domain description: TcdA/TcdB toxin, N-terminal helical domain
Occurring in:
  1. Glucosyltransferase TcdB
IPR020972
Domain description: Dermonecrotic/RTX toxin, membrane localization domain
Occurring in:
  1. Glucosyltransferase TcdB
IPR029044
Domain description: Nucleotide-diphospho-sugar transferases
Occurring in:
  1. Glucosyltransferase TcdB
IPR036393
Domain description: Acetylglutamate kinase-like superfamily
Occurring in:
  1. Glucosyltransferase TcdB

Structure domains

CATH CATH domains
1.10.10.1780
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Arc Repressor Mutant, subunit A
Occurring in:
  1. Glucosyltransferase TcdB
The deposited structure of PDB entry 5uqt contains 2 copies of CATH domain 1.10.10.1780 (Arc Repressor Mutant, subunit A) in Glucosyltransferase TcdB. Showing 1 copy in chain A.
1.20.58.1190
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Occurring in:
  1. Glucosyltransferase TcdB
The deposited structure of PDB entry 5uqt contains 2 copies of CATH domain 1.20.58.1190 (Methane Monooxygenase Hydroxylase; Chain G, domain 1) in Glucosyltransferase TcdB. Showing 1 copy in chain A.

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