Assemblies
Assembly Name:
DNA polymerase beta and DNA
Multimeric state:
hetero tetramer
Accessible surface area:
20805.53 Å2
Buried surface area:
4187.3 Å2
Dissociation area:
977.86
Å2
Dissociation energy (ΔGdiss):
10.48
kcal/mol
Dissociation entropy (TΔSdiss):
11.67
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-119258
Macromolecules
Chain: A
Length: 335 amino acids
Theoretical weight: 38.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 335 amino acids
Theoretical weight: 38.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P06746 (Residues: 1-335; Coverage: 100%)
Pfam:
- Helix-hairpin-helix domain
- Fingers domain of DNA polymerase lambda
- DNA polymerase beta palm
- DNA polymerase beta thumb
- DNA polymerase lambda lyase domain superfamily
- DNA polymerase family X
- DNA-directed DNA polymerase X
- DNA polymerase beta-like, N-terminal domain
- Helix-hairpin-helix DNA-binding motif, class 1
- DNA polymerase family X, beta-like
- DNA polymerase lambda, fingers domain
- DNA polymerase beta, palm domain
- Nucleotidyltransferase superfamily
- DNA polymerase family X, binding site
- DNA polymerase beta, thumb domain
- DNA polymerase, thumb domain superfamily
PDBe-KB: UniProt Coverage View:
P06746
P06746
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Sequence conservation
Name:
DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
Representative chains: T
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 16 nucleotides
Theoretical weight: 4.83 KDa
Representative chains: T
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 16 nucleotides
Theoretical weight: 4.83 KDa
Chain B (auth T)
Interaction interfaces
Name:
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3')
Representative chains: P
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 10 nucleotides
Theoretical weight: 3.12 KDa
Representative chains: P
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 10 nucleotides
Theoretical weight: 3.12 KDa
Chain C (auth P)
Interaction interfaces
Name:
DNA (5'-D(P*GP*TP*CP*GP*G)-3')
Representative chains: D
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 5 nucleotides
Theoretical weight: 1.54 KDa
Representative chains: D
Source organism: synthetic construct [32630]
Expression system: Not provided
Length: 5 nucleotides
Theoretical weight: 1.54 KDa
Chain D (auth D)
Ligand binding sites
Interaction interfaces