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GluA2 bound to antagonist ZK and GSG1L in digitonin, state 1

Source organisms:
Biochemical function: transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Biological process: cellular response to brain-derived neurotrophic factor stimulus
Cellular component: spine synapse

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF07803
Domain description: GSG1-like protein
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
The deposited structure of PDB entry 5wek contains 4 copies of Pfam domain PF07803 (GSG1-like protein) in Germ cell-specific gene 1-like protein. Showing 1 copy in chain A.

PF00060
Domain description: Ligand-gated ion channel
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
The deposited structure of PDB entry 5wek contains 4 copies of Pfam domain PF00060 (Ligand-gated ion channel) in Germ cell-specific gene 1-like protein. Showing 1 copy in chain A.

PF10613
Domain description: Ligated ion channel L-glutamate- and glycine-binding site
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
The deposited structure of PDB entry 5wek contains 4 copies of Pfam domain PF10613 (Ligated ion channel L-glutamate- and glycine-binding site) in Germ cell-specific gene 1-like protein. Showing 1 copy in chain A.

PF01094
Domain description: Receptor family ligand binding region
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
The deposited structure of PDB entry 5wek contains 4 copies of Pfam domain PF01094 (Receptor family ligand binding region) in Germ cell-specific gene 1-like protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001508
Domain description: Ionotropic glutamate receptor, metazoa
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
IPR001320
Domain description: Ionotropic glutamate receptor, C-terminal
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
IPR019594
Domain description: Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
IPR012478
Domain description: GSG1-like
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
IPR015683
Domain description: Ionotropic glutamate receptor
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
IPR001828
Domain description: Receptor, ligand binding region
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2
IPR028082
Domain description: Periplasmic binding protein-like I
Occurring in:
  1. Germ cell-specific gene 1-like protein; Glutamate receptor 2

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