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GluA2 bound to antagonist ZK and GSG1L in digitonin, state 1

Electron Microscopy
4.6Å resolution
PDB entry 5wek coloured by chain, front view.
PDB entry 5wek coloured by chain, side view.
PDB entry 5wek coloured by chain, top view.
Source organisms:
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Germ cell-specific gene 1-like protein, Glutamate receptor 2
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Multimeric state: homo tetramer
Accessible surface area: 159320.34 Å2
Buried surface area: 28522.43 Å2
Dissociation area: 6,634.65 Å2
Dissociation energy (ΔGdiss): 87.46 kcal/mol
Dissociation entropy (TΔSdiss): 19.38 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-112594

Macromolecules

Germ cell-specific gene 1-like protein; Glutamate receptor 2
Chains: A, B, C, D
Length: 1057 amino acids
Theoretical weight: 117.47 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P19491 (Residues: 25-847; Coverage: 95%)
  • Canonical: D3Z7H4 (Residues: 2-238; Coverage: 74%)
    • nullnull
Gene names: GluA2, Glur2, Gria2, Gsg1l
Pfam:
InterPro:
Germ cell-specific gene 1-like protein in PDB entry 5wek, assembly 1, front view.
Germ cell-specific gene 1-like protein in PDB entry 5wek, assembly 1, side view.
Germ cell-specific gene 1-like protein in PDB entry 5wek, assembly 1, top view.
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