Structure analysis

Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317

X-ray diffraction
1.1Å resolution
Source organism: Homo sapiens
Assembly composition:
homo pentadecamer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo pentadecamer
Accessible surface area: 4375.33 Å2
Buried surface area: 8866.12 Å2
Dissociation area: 370.64 Å2
Dissociation energy (ΔGdiss): 2.58 kcal/mol
Dissociation entropy (TΔSdiss): 5.95 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-171563

Macromolecules

Chain: A
Length: 6 amino acids
Theoretical weight: 642 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13148 (Residues: 312-317; Coverage: 1%)
Gene names: TARDBP, TDP43

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