5wk2

X-ray diffraction
1.5Å resolution

CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116

Released:
Source organism: Homo sapiens
Primary publication:
Structural insights into chemokine CCL17 recognition by antibody M116.
OpenAccess logo Biochem Biophys Rep 13 27-31 (2018)
PMID: 29264403

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-231468 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
M116 LIGHT CHAIN Chain: L
Molecule details ›
Chain: L
Length: 220 amino acids
Theoretical weight: 24.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
M116 HEAVY CHAIN Chain: H
Molecule details ›
Chain: H
Length: 230 amino acids
Theoretical weight: 24.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 53.74Å b: 64.92Å c: 73.79Å
α: 90° β: 107.29° γ: 90°
R-values:
R R work R free
0.18 0.18 0.208
Expression system: Homo sapiens