Structure analysis

Structure of fungal meroterpenoid isomerase Trt14 complexed with terretonin D

X-ray diffraction
2.3Å resolution
Source organism: Aspergillus terreus NIH2624
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 13202.9 Å2
Buried surface area: 2443.46 Å2
Dissociation area: 1,146.12 Å2
Dissociation energy (ΔGdiss): 11.97 kcal/mol
Dissociation entropy (TΔSdiss): 12.03 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-555354
Assembly 2
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Multimeric state: homo dimer
Accessible surface area: 13080.86 Å2
Buried surface area: 2441.54 Å2
Dissociation area: 1,145.83 Å2
Dissociation energy (ΔGdiss): 10.17 kcal/mol
Dissociation entropy (TΔSdiss): 12.01 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-555354
Assembly 3
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Multimeric state: homo dimer
Accessible surface area: 12894.07 Å2
Buried surface area: 2485.89 Å2
Dissociation area: 1,171.38 Å2
Dissociation energy (ΔGdiss): 11.96 kcal/mol
Dissociation entropy (TΔSdiss): 12.01 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-555354

Macromolecules

Chains: A, B, C, D, E, F
Length: 162 amino acids
Theoretical weight: 18.32 KDa
Source organism: Aspergillus terreus NIH2624
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0C8A2 (Residues: 1-142; Coverage: 100%)
Gene names: ATEG_10082, trt14

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