› › Structure analysis

Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS

X-ray diffraction
3.76Å resolution
PDB entry 5xat coloured by chain, front view.
PDB entry 5xat coloured by chain, side view.
PDB entry 5xat coloured by chain, top view.
Source organism: Klebsiella pneumoniae
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Citrate/sodium symporter
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 30222.35 Å2
Buried surface area: 6979.03 Å2
Dissociation area: 2,845.44 Å2
Dissociation energy (ΔGdiss): 51.93 kcal/mol
Dissociation entropy (TΔSdiss): 14.17 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-152038
Assembly 2
Download    3D Visualisation
Assembly Name: Citrate/sodium symporter
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 29107.35 Å2
Buried surface area: 6531.66 Å2
Dissociation area: 2,815.1 Å2
Dissociation energy (ΔGdiss): 52.78 kcal/mol
Dissociation entropy (TΔSdiss): 14.5 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-152038

Macromolecules

Citrate/sodium symporter
Chains: A, B, C, D
Length: 438 amino acids
Theoretical weight: 46.67 KDa
Source organism: Klebsiella pneumoniae
Expression system: Escherichia coli
UniProt:
  • Canonical: P31602 (Residues: 13-446; Coverage: 97%)
Gene name: citS
Pfam: 2-hydroxycarboxylate transporter family
InterPro:
Citrate-sodium symporter in PDB entry 5xat, assembly 1, front view.
Citrate-sodium symporter in PDB entry 5xat, assembly 1, side view.
Citrate-sodium symporter in PDB entry 5xat, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links