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Crystal structure of Plasmodium falciparum aminopeptidase N with Magnesium bound to active site Zinc

X-ray diffraction
1.56Å resolution
PDB entry 5y1w coloured by chain, front view.
PDB entry 5y1w coloured by chain, side view.
PDB entry 5y1w coloured by chain, top view.
Source organism: Plasmodium falciparum FcB1/Columbia
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: p68 form
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Multimeric state: monomeric
Accessible surface area: 34733.47 Å2
Buried surface area: 687.0 Å2
Dissociation area: 129.54 Å2
Dissociation energy (ΔGdiss): 1.12 kcal/mol
Dissociation entropy (TΔSdiss): 0.88 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-132164

Macromolecules

p68 form
Chain: A
Length: 914 amino acids
Theoretical weight: 106.29 KDa
Source organism: Plasmodium falciparum FcB1/Columbia
Expression system: Escherichia coli
UniProt:
  • Canonical: O96935 (Residues: 195-1085; Coverage: 85%)
Gene names: M1AAP, MAL13P1.56, PF3D7_1311800
Pfam:
InterPro:
CATH:
p68 form in PDB entry 5y1w, assembly 1, front view.
p68 form in PDB entry 5y1w, assembly 1, side view.
p68 form in PDB entry 5y1w, assembly 1, top view.
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