Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
ATP + H(2)O = ADP + phosphate
ATP + a protein = ADP + a phosphoprotein
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero 33-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120375 (preferred)
Entry contents:
31 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (33 distinct):
DNA-directed RNA polymerase II subunit RPB1
Molecule details ›
Chain: A
Length: 1970 amino acids
Theoretical weight: 217.42 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 1970 amino acids
Theoretical weight: 217.42 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P24928 (Residues: 1-1970; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase II subunit RPB2
Molecule details ›
Chain: B
Length: 1174 amino acids
Theoretical weight: 134.07 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 1174 amino acids
Theoretical weight: 134.07 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P30876 (Residues: 1-1174; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase II subunit RPB3
DNA-directed RNA polymerase II subunit RPB4
DNA-directed RNA polymerases I, II, and III subunit RPABC1
DNA-directed RNA polymerases I, II, and III subunit RPABC2
DNA-directed RNA polymerase II subunit RPB7
DNA-directed RNA polymerases I, II, and III subunit RPABC3
DNA-directed RNA polymerase II subunit RPB9
DNA-directed RNA polymerases I, II, and III subunit RPABC5
DNA-directed RNA polymerase II subunit RPB11-a
DNA-directed RNA polymerases I, II, and III subunit RPABC4
Transcription initiation factor IIB
Transcription initiation factor IIA subunit 1
Transcription initiation factor IIA subunit 2
TATA-box-binding protein
General transcription factor IIE subunit 1
Transcription initiation factor IIE subunit beta
General transcription factor IIF subunit 1
General transcription factor IIF subunit 2
Transcription elongation factor A protein 1
General transcription and DNA repair factor IIH helicase subunit XPD
General transcription factor IIH subunit 1
General transcription factor IIH subunit 4
CDK-activating kinase assembly factor MAT1
General transcription factor IIH subunit 3
General transcription factor IIH subunit 5
General transcription factor IIH subunit 2
General transcription and DNA repair factor IIH helicase/translocase subunit XPB
Cyclin-dependent kinase 7
Cyclin-H
