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Orthorhombic trypsin cryocooled to 100 K with 20% xylose as cryoprotectant

X-ray diffraction
2.4Å resolution
PDB entry 6b6o coloured by chain, front view.
PDB entry 6b6o coloured by chain, side view.
PDB entry 6b6o coloured by chain, top view.
Source organism: Bos taurus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serine protease 1
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Multimeric state: monomeric
Accessible surface area: 9125.44 Å2
Buried surface area: 1292.98 Å2
Dissociation area: 107.31 Å2
Dissociation energy (ΔGdiss): -2.47 kcal/mol
Dissociation entropy (TΔSdiss): 2.01 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-133319

Macromolecules

Serine protease 1
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
Expression system: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
Serine protease 1 in PDB entry 6b6o, assembly 1, front view.
Serine protease 1 in PDB entry 6b6o, assembly 1, side view.
Serine protease 1 in PDB entry 6b6o, assembly 1, top view.
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