› 6c0a

Solution NMR

Actinin-1 EF-Hand bound to the Cav1.2 IQ Motif

Released:
DOI: 10.2210/pdb6c0a/pdb
PDB entry 6c0a coloured by chain, ensemble of 4 models, front view.
PDB entry 6c0a coloured by chain, ensemble of 4 models, side view.
PDB entry 6c0a coloured by chain, ensemble of 4 models, top view.
Source organisms:
Entry authors: Turner ML, Ames JB

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171835 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-actinin-1 Chain: A
Molecule details ›
Chain: A
Length: 71 amino acids
Theoretical weight: 7.85 KDa
Source organism: Mus musculus
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q7TPR4 (Residues: 822-892; Coverage: 8%)
Gene name: Actn1
Sequence domains: Ca2+ insensitive EF hand
Structure domains: EF-hand
Voltage-dependent L-type calcium channel subunit alpha-1C Chain: B
Molecule details ›
Chain: B
Length: 23 amino acids
Theoretical weight: 2.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13936 (Residues: 1664-1686; Coverage: 1%)
Gene names: CACH2, CACN2, CACNA1C, CACNL1A1, CCHL1A1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 63%
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli 'BL21-Gold(DE3)pLysS AG'
  • Not provided

Quick links