Function and Biology

Actinin-1 EF-Hand bound to the Cav1.2 IQ Motif

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF08726
Domain description: Ca2+ insensitive EF hand
Occurring in:
  1. Alpha-actinin-1
The deposited structure of PDB entry 6c0a contains 1 copy of Pfam domain PF08726 (Ca2+ insensitive EF hand) in Alpha-actinin-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR014873
Domain description: Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
Occurring in:
  1. Voltage-dependent L-type calcium channel subunit alpha-1C
IPR014837
Domain description: EF-hand, Ca insensitive
Occurring in:
  1. Alpha-actinin-1
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Alpha-actinin-1

Structure domain

CATH CATH domain
1.10.238.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: EF-hand
Occurring in:
  1. Alpha-actinin-1
The deposited structure of PDB entry 6c0a contains 1 copy of CATH domain 1.10.238.10 (Recoverin; domain 1) in Alpha-actinin-1. Showing 1 copy in chain A.