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PI(4,5)P2 bound full-length rbTRPV5

Electron Microscopy
4Å resolution
PDB entry 6dmu coloured by chain, front view.
PDB entry 6dmu coloured by chain, side view.
PDB entry 6dmu coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Transient receptor potential cation channel subfamily V member 5
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Multimeric state: homo tetramer
Accessible surface area: 129301.92 Å2
Buried surface area: 25738.63 Å2
Dissociation area: 11,309.7 Å2
Dissociation energy (ΔGdiss): 203.68 kcal/mol
Dissociation entropy (TΔSdiss): 50.55 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-195036

Macromolecules

Transient receptor potential cation channel subfamily V member 5
Chains: A, B, C, D
Length: 730 amino acids
Theoretical weight: 82.9 KDa
Source organism: Oryctolagus cuniculus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q9XSM3 (Residues: 1-730; Coverage: 100%)
Gene names: Ecac1, Trpv5
Pfam:
InterPro:
Transient receptor potential cation channel subfamily V member 5 in PDB entry 6dmu, assembly 1, front view.
Transient receptor potential cation channel subfamily V member 5 in PDB entry 6dmu, assembly 1, side view.
Transient receptor potential cation channel subfamily V member 5 in PDB entry 6dmu, assembly 1, top view.
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