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Calmodulin-bound full-length rbTRPV5

Electron Microscopy
4.4Å resolution
PDB entry 6dmw coloured by chain, front view.
PDB entry 6dmw coloured by chain, side view.
PDB entry 6dmw coloured by chain, top view.
Source organisms:
Assembly composition:
hetero pentamer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Calmodulin-1 and Transient receptor potential cation channel subfamily V member 5
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Multimeric state: hetero pentamer
Accessible surface area: 131786.07 Å2
Buried surface area: 27965.11 Å2
Dissociation area: 2,310.16 Å2
Dissociation energy (ΔGdiss): 18.31 kcal/mol
Dissociation entropy (TΔSdiss): 12.42 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-144033

Macromolecules

Transient receptor potential cation channel subfamily V member 5
Chains: A, B, C, D
Length: 730 amino acids
Theoretical weight: 82.9 KDa
Source organism: Oryctolagus cuniculus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q9XSM3 (Residues: 1-730; Coverage: 100%)
Gene names: Ecac1, Trpv5
Pfam:
InterPro:
Transient receptor potential cation channel subfamily V member 5 in PDB entry 6dmw, assembly 1, front view.
Transient receptor potential cation channel subfamily V member 5 in PDB entry 6dmw, assembly 1, side view.
Transient receptor potential cation channel subfamily V member 5 in PDB entry 6dmw, assembly 1, top view.
Molecule details ›

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Calmodulin-1
Chain: E
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP29 (Residues: 1-149; Coverage: 100%)
Gene names: CaMI, Calm, Calm1, Cam, Cam1
Pfam: EF-hand domain pair
InterPro:
Calmodulin-1 in PDB entry 6dmw, assembly 1, front view.
Calmodulin-1 in PDB entry 6dmw, assembly 1, side view.
Calmodulin-1 in PDB entry 6dmw, assembly 1, top view.
Molecule details ›

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