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Crystal structure of KDM4D with tetrazolhydrazide compound 3

X-ray diffraction
1.35Å resolution
PDB entry 6etw coloured by chain, front view.
PDB entry 6etw coloured by chain, side view.
PDB entry 6etw coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Lysine-specific demethylase 4D
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Multimeric state: monomeric
Accessible surface area: 15079.1 Å2
Buried surface area: 1619.11 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-179408

Macromolecules

Lysine-specific demethylase 4D
Chain: A
Length: 342 amino acids
Theoretical weight: 39.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6B0I6 (Residues: 1-342; Coverage: 65%)
Gene names: JHDM3D, JMJD2D, KDM4D
Pfam:
InterPro:
CATH: Cupin
Lysine-specific demethylase 4D in PDB entry 6etw, assembly 1, front view.
Lysine-specific demethylase 4D in PDB entry 6etw, assembly 1, side view.
Lysine-specific demethylase 4D in PDB entry 6etw, assembly 1, top view.
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