Structure analysis

Crystal structure of BAZ2A PHD zinc finger in complex with H3 10-mer AA mutant peptide

X-ray diffraction
2Å resolution
Source organism: Homo sapiens
Assemblies composition:
hetero dimer (preferred)
monomeric
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 4349.35 Å2
Buried surface area: 785.44 Å2
Dissociation area: 348.1 Å2
Dissociation energy (ΔGdiss): 2.08 kcal/mol
Dissociation entropy (TΔSdiss): 5.72 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-166715
Assembly 2
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Multimeric state: monomeric
Accessible surface area: 3904.65 Å2
Buried surface area: 86.58 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-193785
Assembly 3
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Multimeric state: hetero dimer
Accessible surface area: 4289.49 Å2
Buried surface area: 839.3 Å2
Dissociation area: 363.29 Å2
Dissociation energy (ΔGdiss): 2.07 kcal/mol
Dissociation entropy (TΔSdiss): 5.67 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-166715
Assembly 4
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Multimeric state: hetero dimer
Accessible surface area: 4304.29 Å2
Buried surface area: 835.44 Å2
Dissociation area: 357.19 Å2
Dissociation energy (ΔGdiss): 2.19 kcal/mol
Dissociation entropy (TΔSdiss): 5.61 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-166715

Macromolecules

Chains: A, B, C, D
Length: 58 amino acids
Theoretical weight: 6.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UIF9 (Residues: 1673-1728; Coverage: 3%)
Gene names: BAZ2A, KIAA0314, TIP5
Pfam: PHD-finger
InterPro:
CATH: Zinc/RING finger domain, C3HC4 (zinc finger)

Search similar proteins

Chains: E, F, G
Length: 10 amino acids
Theoretical weight: 1.04 KDa
Source organism: Homo sapiens
Expression system: Not provided

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