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Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

Solution NMR
PDB entry 6fwn coloured by chain, ensemble of 20 models, front view.
PDB entry 6fwn coloured by chain, ensemble of 20 models, side view.
PDB entry 6fwn coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: von Willebrand factor
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Multimeric state: monomeric
Accessible surface area: 6680.66 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-137563

Macromolecules

von Willebrand factor
Chain: A
Length: 85 amino acids
Theoretical weight: 9.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04275 (Residues: 2497-2577; Coverage: 3%)
Gene names: F8VWF, VWF
von Willebrand factor in PDB entry 6fwn, assembly 1, front view.
von Willebrand factor in PDB entry 6fwn, assembly 1, side view.
von Willebrand factor in PDB entry 6fwn, assembly 1, top view.
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