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Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)

Electron Microscopy
3.02Å resolution
PDB entry 6fyy coloured by chain, front view.
PDB entry 6fyy coloured by chain, side view.
PDB entry 6fyy coloured by chain, top view.
Source organisms:
Assembly composition:
hetero 47-mer (preferred)
Entry contents: 44 distinct polypeptide molecules
3 distinct RNA molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Eukaryotic translation initiation factor 2 complex and RNA
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Multimeric state: hetero 47-mer
Accessible surface area: 528755.92 Å2
Buried surface area: 276647.77 Å2
Dissociation area: 1,200.43 Å2
Dissociation energy (ΔGdiss): 7.12 kcal/mol
Dissociation entropy (TΔSdiss): 15.2 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-108171

Macromolecules

Small ribosomal subunit protein uS2
Chain: A
Length: 254 amino acids
Theoretical weight: 28.26 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CN12 (Residues: 1-254; Coverage: 100%)
Gene names: KLLA0E16171g, RPS0
Pfam: Ribosomal protein S2
InterPro:
Small ribosomal subunit protein uS2 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS2 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS2 in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein eS1
Chain: B
Length: 255 amino acids
Theoretical weight: 29.01 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CWD0 (Residues: 1-255; Coverage: 100%)
Gene names: KLLA0B05060g, RPS1
Pfam: Ribosomal S3Ae family
InterPro:
Small ribosomal subunit protein eS1 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein eS1 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein eS1 in PDB entry 6fyy, assembly 1, top view.
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S5 DRBM domain-containing protein
Chain: C
Length: 259 amino acids
Theoretical weight: 27.65 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CKL3 (Residues: 1-259; Coverage: 100%)
Gene name: KLLA0_F09812g
Pfam:
InterPro:
S5 DRBM domain-containing protein in PDB entry 6fyy, assembly 1, front view.
S5 DRBM domain-containing protein in PDB entry 6fyy, assembly 1, side view.
S5 DRBM domain-containing protein in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S3
Chain: D
Length: 237 amino acids
Theoretical weight: 26.3 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CRK7 (Residues: 1-237; Coverage: 100%)
Gene name: KLLA0_D08305g
Pfam:
InterPro:
40S ribosomal protein S3 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S3 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S3 in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S4
Chain: E
Length: 261 amino acids
Theoretical weight: 29.62 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CWJ2 (Residues: 1-261; Coverage: 100%)
Gene name: KLLA0_B03652g
Pfam:
InterPro:
40S ribosomal protein S4 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S4 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S4 in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein uS7 domain-containing protein
Chain: F
Length: 227 amino acids
Theoretical weight: 25.39 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CRA3 (Residues: 1-227; Coverage: 100%)
Gene name: KLLA0_D10659g
Pfam: Ribosomal protein S7p/S5e
InterPro:
Small ribosomal subunit protein uS7 domain-containing protein in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS7 domain-containing protein in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS7 domain-containing protein in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein eS6
Chain: G
Length: 236 amino acids
Theoretical weight: 26.97 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CM04 (Residues: 1-236; Coverage: 100%)
Gene names: KLLA0E24090g, RPS6
Pfam: Ribosomal protein S6e
InterPro:
Small ribosomal subunit protein eS6 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein eS6 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein eS6 in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S7
Chain: H
Length: 190 amino acids
Theoretical weight: 21.74 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CTD6 (Residues: 1-190; Coverage: 100%)
Gene name: KLLA0_C13519g
Pfam: Ribosomal protein S7e
InterPro:
40S ribosomal protein S7 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S7 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S7 in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S8
Chain: I
Length: 201 amino acids
Theoretical weight: 22.64 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CMG3 (Residues: 1-201; Coverage: 100%)
Gene name: KLLA0_E20461g
Pfam: Ribosomal protein S8e
InterPro:
40S ribosomal protein S8 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S8 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S8 in PDB entry 6fyy, assembly 1, top view.
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KLLA0E23673p
Chain: J
Length: 188 amino acids
Theoretical weight: 21.59 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CM18 (Residues: 1-188; Coverage: 100%)
Gene name: KLLA0_E23673g
Pfam:
InterPro:
KLLA0E23673p in PDB entry 6fyy, assembly 1, front view.
KLLA0E23673p in PDB entry 6fyy, assembly 1, side view.
KLLA0E23673p in PDB entry 6fyy, assembly 1, top view.
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Plectin/eS10 N-terminal domain-containing protein
Chain: K
Length: 106 amino acids
Theoretical weight: 12.58 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CVZ5 (Residues: 1-106; Coverage: 100%)
Gene name: KLLA0_B08173g
Pfam: Plectin/S10 domain
InterPro:
Plectin/eS10 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, front view.
Plectin/eS10 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, side view.
Plectin/eS10 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein uS17 N-terminal domain-containing protein
Chain: L
Length: 156 amino acids
Theoretical weight: 17.84 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CX80 (Residues: 1-156; Coverage: 100%)
Gene name: KLLA0_A10483g
Pfam:
InterPro:
Small ribosomal subunit protein uS17 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS17 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS17 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S12
Chain: M
Length: 134 amino acids
Theoretical weight: 14.47 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CLU4 (Residues: 1-134; Coverage: 100%)
Gene name: KLLA0_F00352g
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
40S ribosomal protein S12 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S12 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S12 in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein uS15 N-terminal domain-containing protein
Chain: N
Length: 151 amino acids
Theoretical weight: 16.99 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CJK0 (Residues: 1-151; Coverage: 100%)
Gene name: KLLA0_F18040g
Pfam:
InterPro:
Small ribosomal subunit protein uS15 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS15 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS15 N-terminal domain-containing protein in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein uS11
Chain: O
Length: 137 amino acids
Theoretical weight: 14.53 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: P27069 (Residues: 1-137; Coverage: 100%)
Gene names: CRY1, KLLA0B07623g, RPS14
Pfam: Ribosomal protein S11
InterPro:
Small ribosomal subunit protein uS11 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS11 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS11 in PDB entry 6fyy, assembly 1, top view.
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Rps15
Chain: P
Length: 142 amino acids
Theoretical weight: 15.99 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CKV4 (Residues: 1-142; Coverage: 100%)
Gene name: KLLA0_F07843g
Pfam: Ribosomal protein S19
InterPro:
Rps15 in PDB entry 6fyy, assembly 1, front view.
Rps15 in PDB entry 6fyy, assembly 1, side view.
Rps15 in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein uS9
Chain: Q
Length: 143 amino acids
Theoretical weight: 15.87 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q875N2 (Residues: 1-143; Coverage: 100%)
Gene names: KLLA0E22077g, RPS16
Pfam: Ribosomal protein S9/S16
InterPro:
Small ribosomal subunit protein uS9 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS9 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS9 in PDB entry 6fyy, assembly 1, top view.
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KLLA0B01474p
Chain: R
Length: 136 amino acids
Theoretical weight: 15.72 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CWU3 (Residues: 1-136; Coverage: 100%)
Gene name: KLLA0_B01474g
Pfam: Ribosomal S17
InterPro:
KLLA0B01474p in PDB entry 6fyy, assembly 1, front view.
KLLA0B01474p in PDB entry 6fyy, assembly 1, side view.
KLLA0B01474p in PDB entry 6fyy, assembly 1, top view.
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KLLA0B01562p
Chain: S
Length: 146 amino acids
Theoretical weight: 17.08 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CWT9 (Residues: 1-146; Coverage: 100%)
Gene name: KLLA0_B01562g
Pfam: Ribosomal protein S13/S18
InterPro:
KLLA0B01562p in PDB entry 6fyy, assembly 1, front view.
KLLA0B01562p in PDB entry 6fyy, assembly 1, side view.
KLLA0B01562p in PDB entry 6fyy, assembly 1, top view.
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KLLA0A07194p
Chain: T
Length: 144 amino acids
Theoretical weight: 15.88 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CXM0 (Residues: 1-144; Coverage: 100%)
Gene name: KLLA0_A07194g
Pfam: Ribosomal protein S19e
InterPro:
KLLA0A07194p in PDB entry 6fyy, assembly 1, front view.
KLLA0A07194p in PDB entry 6fyy, assembly 1, side view.
KLLA0A07194p in PDB entry 6fyy, assembly 1, top view.
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Small ribosomal subunit protein uS10 domain-containing protein
Chain: U
Length: 117 amino acids
Theoretical weight: 13.34 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CIM1 (Residues: 1-117; Coverage: 100%)
Gene name: KLLA0_F25542g
Pfam: Ribosomal protein S10p/S20e
InterPro:
Small ribosomal subunit protein uS10 domain-containing protein in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS10 domain-containing protein in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS10 domain-containing protein in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Small ribosomal subunit protein eS21
Chain: V
Length: 87 amino acids
Theoretical weight: 9.8 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CXT6 (Residues: 1-87; Coverage: 100%)
Gene names: KLLA0A05700g, RPS21
Pfam: Ribosomal protein S21e
InterPro:
Small ribosomal subunit protein eS21 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein eS21 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein eS21 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Small ribosomal subunit protein uS8
Chain: W
Length: 130 amino acids
Theoretical weight: 14.65 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CW21 (Residues: 1-130; Coverage: 100%)
Gene names: KLLA0B07601g, RPS22
Pfam: Ribosomal protein S8
InterPro:
Small ribosomal subunit protein uS8 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS8 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS8 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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40S ribosomal protein S23
Chain: X
Length: 145 amino acids
Theoretical weight: 16.05 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: F2Z602 (Residues: 1-145; Coverage: 100%)
Gene name: KLLA0_B11231g
Pfam: Ribosomal protein S12/S23
InterPro:
40S ribosomal protein S23 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S23 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S23 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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40S ribosomal protein S24
Chain: Y
Length: 135 amino acids
Theoretical weight: 15.19 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CU44 (Residues: 1-135; Coverage: 100%)
Gene name: KLLA0_C07755g
Pfam: Ribosomal protein S24e
InterPro:
40S ribosomal protein S24 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S24 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S24 in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S25
Chain: Z
Length: 108 amino acids
Theoretical weight: 12 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CW78 (Residues: 1-108; Coverage: 100%)
Gene name: KLLA0_B06182g
Pfam: S25 ribosomal protein
InterPro: Small ribosomal subunit protein eS25
40S ribosomal protein S25 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S25 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S25 in PDB entry 6fyy, assembly 1, top view.
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40S ribosomal protein S26
Chain: a
Length: 119 amino acids
Theoretical weight: 13.54 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CS01 (Residues: 1-119; Coverage: 100%)
Gene name: KLLA0_D05115g
Pfam: Ribosomal protein S26e
InterPro:
40S ribosomal protein S26 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S26 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S26 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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40S ribosomal protein S27
Chain: b
Length: 82 amino acids
Theoretical weight: 8.88 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CNL2 (Residues: 1-82; Coverage: 100%)
Gene name: KLLA0_E11661g
Pfam: Ribosomal protein S27
InterPro:
40S ribosomal protein S27 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S27 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S27 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Small ribosomal subunit protein eS28
Chain: c
Length: 67 amino acids
Theoretical weight: 7.55 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: P33285 (Residues: 1-67; Coverage: 100%)
Gene names: KLLA0F20383g, RPS28
Pfam: Ribosomal protein S28e
InterPro:
Small ribosomal subunit protein eS28 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein eS28 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein eS28 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Small ribosomal subunit protein uS14
Chain: d
Length: 56 amino acids
Theoretical weight: 6.66 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CPG3 (Residues: 1-56; Coverage: 100%)
Gene names: KLLA0E05071g, RPS29
Pfam: Ribosomal protein S14p/S29e
InterPro:
Small ribosomal subunit protein uS14 in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein uS14 in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein uS14 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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40S ribosomal protein S30
Chain: e
Length: 63 amino acids
Theoretical weight: 7.14 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CUH5 (Residues: 1-63; Coverage: 100%)
Gene name: KLLA0_C04809g
Pfam: Ribosomal protein S30
InterPro: Small ribosomal subunit protein eS30
40S ribosomal protein S30 in PDB entry 6fyy, assembly 1, front view.
40S ribosomal protein S30 in PDB entry 6fyy, assembly 1, side view.
40S ribosomal protein S30 in PDB entry 6fyy, assembly 1, top view.
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Ubiquitin-ribosomal protein eS31 fusion protein
Chain: f
Length: 150 amino acids
Theoretical weight: 17.11 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: P69061 (Residues: 1-150; Coverage: 100%)
Gene names: KLLA0D18304g, ubi3
Pfam:
InterPro:
Ubiquitin-ribosomal protein eS31 fusion protein in PDB entry 6fyy, assembly 1, front view.
Ubiquitin-ribosomal protein eS31 fusion protein in PDB entry 6fyy, assembly 1, side view.
Ubiquitin-ribosomal protein eS31 fusion protein in PDB entry 6fyy, assembly 1, top view.
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Asc1
Chain: g
Length: 326 amino acids
Theoretical weight: 35.83 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: Q6CNI7 (Residues: 1-326; Coverage: 100%)
Gene name: KLLA0_E12277g
Pfam: WD domain, G-beta repeat
InterPro:
Asc1 in PDB entry 6fyy, assembly 1, front view.
Asc1 in PDB entry 6fyy, assembly 1, side view.
Asc1 in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Small ribosomal subunit protein eS32A
Chain: h
Length: 25 amino acids
Theoretical weight: 3.35 KDa
Source organism: Kluyveromyces lactis NRRL Y-1140
UniProt:
  • Canonical: P0CX86 (Residues: 1-25; Coverage: 100%)
Gene names: D1290, RPL41A, RPL47A, YDL184C, YL41A
Pfam: Ribosomal protein L41
InterPro: Large ribosomal subunit protein eS32
Small ribosomal subunit protein eS32A in PDB entry 6fyy, assembly 1, front view.
Small ribosomal subunit protein eS32A in PDB entry 6fyy, assembly 1, side view.
Small ribosomal subunit protein eS32A in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 1A
Chain: i
Length: 153 amino acids
Theoretical weight: 17.46 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P38912 (Residues: 1-153; Coverage: 100%)
Gene names: TIF11, YM8156.02C, YMR260C
Pfam: Translation initiation factor 1A / IF-1
InterPro:
Eukaryotic translation initiation factor 1A in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 1A in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 1A in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Eukaryotic translation initiation factor 2 subunit alpha
Chain: j
Length: 304 amino acids
Theoretical weight: 34.76 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P20459 (Residues: 1-304; Coverage: 100%)
Gene names: J1429, SUI2, TIF211, YJR007W
Pfam:
InterPro:
Eukaryotic translation initiation factor 2 subunit alpha in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 2 subunit alpha in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 2 subunit alpha in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Eukaryotic translation initiation factor 2 subunit gamma
Chain: k
Length: 527 amino acids
Theoretical weight: 57.94 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P32481 (Residues: 1-527; Coverage: 100%)
Gene names: GCD11, SUI4, TIF213, YER025W
Pfam:
InterPro:
Eukaryotic translation initiation factor 2 subunit gamma in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 2 subunit gamma in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 2 subunit gamma in PDB entry 6fyy, assembly 1, top view.
Molecule details ›

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Eukaryotic translation initiation factor 2 subunit beta
Chain: l
Length: 285 amino acids
Theoretical weight: 31.63 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P09064 (Residues: 1-285; Coverage: 100%)
Gene names: SUI3, TIF212, YPL237W
Pfam: Domain found in IF2B/IF5
InterPro:
Eukaryotic translation initiation factor 2 subunit beta in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 2 subunit beta in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 2 subunit beta in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 5
Chain: m
Length: 405 amino acids
Theoretical weight: 45.32 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P38431 (Residues: 1-405; Coverage: 100%)
Gene names: TIF5, YP3085.05, YPR041W
Pfam:
InterPro:
Eukaryotic translation initiation factor 5 in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 5 in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 5 in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 3 subunit A
Chain: o
Length: 964 amino acids
Theoretical weight: 110.52 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38249 (Residues: 1-964; Coverage: 100%)
Gene names: RPG1, TIF32, YBR0734, YBR079C
Pfam: eIF3a, PCI domain, TPR-like region
InterPro:
Eukaryotic translation initiation factor 3 subunit A in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 3 subunit A in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 3 subunit A in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 3 subunit B
Chain: p
Length: 763 amino acids
Theoretical weight: 88.24 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P06103 (Residues: 1-763; Coverage: 100%)
Gene names: CDC63, PRT1, YOR361C
Pfam:
InterPro:
Eukaryotic translation initiation factor 3 subunit B in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 3 subunit B in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 3 subunit B in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 3 subunit C
Chain: q
Length: 812 amino acids
Theoretical weight: 86.54 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P32497 (Residues: 251-812; Coverage: 69%)
Gene names: NIP1, YM9924.01C, YM9952.11C, YMR309C
Pfam:
InterPro:
Eukaryotic translation initiation factor 3 subunit C in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 3 subunit C in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 3 subunit C in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 3 subunit G
Chain: r
Length: 274 amino acids
Theoretical weight: 30.52 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: A6ZZ25 (Residues: 1-274; Coverage: 100%)
Gene names: SCY_1313, TIF35
Pfam:
InterPro:
Eukaryotic translation initiation factor 3 subunit G in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 3 subunit G in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 3 subunit G in PDB entry 6fyy, assembly 1, top view.
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Eukaryotic translation initiation factor 3 subunit I
Chain: s
Length: 347 amino acids
Theoretical weight: 38.8 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: A6ZMK5 (Residues: 1-347; Coverage: 100%)
Gene names: SCY_4321, TIF34
Pfam: WD domain, G-beta repeat
InterPro:
Eukaryotic translation initiation factor 3 subunit I in PDB entry 6fyy, assembly 1, front view.
Eukaryotic translation initiation factor 3 subunit I in PDB entry 6fyy, assembly 1, side view.
Eukaryotic translation initiation factor 3 subunit I in PDB entry 6fyy, assembly 1, top view.
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RNA chain 1
Name: tRNAi
Representative chains: 1
Length: 76 nucleotides
Theoretical weight: 24.8 KDa
Rfam: tRNA
tRNAi in PDB entry 6fyy, assembly 1, front view.
tRNAi in PDB entry 6fyy, assembly 1, side view.
tRNAi in PDB entry 6fyy, assembly 1, top view.
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RNA chain 2
Name: 18S Ribosomal RNA
Representative chains: 2
Length: 1798 nucleotides
Theoretical weight: 579.45 KDa
Rfam: Eukaryotic small subunit ribosomal RNA
18S Ribosomal RNA in PDB entry 6fyy, assembly 1, front view.
18S Ribosomal RNA in PDB entry 6fyy, assembly 1, side view.
18S Ribosomal RNA in PDB entry 6fyy, assembly 1, top view.
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RNA chain 3
Name: mRNA (31-MER)
Representative chains: 3
Length: 49 nucleotides
Theoretical weight: 15.34 KDa
mRNA (31-MER) in PDB entry 6fyy, assembly 1, front view.
mRNA (31-MER) in PDB entry 6fyy, assembly 1, side view.
mRNA (31-MER) in PDB entry 6fyy, assembly 1, top view.
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