Assemblies
Assembly Name:
Pyruvate kinase PKM
Multimeric state:
homo tetramer
Accessible surface area:
67311.61 Å2
Buried surface area:
17111.88 Å2
Dissociation area:
2,228.93
Å2
Dissociation energy (ΔGdiss):
21.27
kcal/mol
Dissociation entropy (TΔSdiss):
15.88
kcal/mol
Symmetry number:
4
PDBe Complex ID:
PDB-CPX-146985
Macromolecules
Chains: A, B, C, D
Length: 551 amino acids
Theoretical weight: 60.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 551 amino acids
Theoretical weight: 60.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P14618 (Residues: 1-531; Coverage: 100%)
Pfam:
InterPro:
- Rossmann-like alpha/beta/alpha sandwich fold
- Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily
- Pyruvate kinase
- Pyruvate kinase, C-terminal domain superfamily
- Pyruvate kinase, barrel
- Pyruvate kinase-like domain superfamily
- Pyruvate kinase-like, insert domain superfamily
- Pyruvate kinase, insert domain superfamily
- Pyruvate kinase, active site
- Pyruvate kinase, C-terminal