Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125641 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Cyclin-dependent kinase 1
Molecule details ›
Chain: A
Length: 302 amino acids
Theoretical weight: 34.55 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 302 amino acids
Theoretical weight: 34.55 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P06493 (Residues: 1-297; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
G2/mitotic-specific cyclin-B1
Molecule details ›
Chain: B
Length: 273 amino acids
Theoretical weight: 31.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Cyclin-like
Length: 273 amino acids
Theoretical weight: 31.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P14635 (Residues: 165-433; Coverage: 62%)
Sequence domains:
Structure domains: Cyclin-like
Cyclin-dependent kinases regulatory subunit
Ligands and Environments
1 bound ligand:
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
DIAMOND BEAMLINE I03
Spacegroup:
P212121
Expression systems:
- Spodoptera frugiperda
- Escherichia coli BL21(DE3)
- Escherichia coli
