Assemblies
Assembly Name:
Cyclin-A2 and Cyclin-dependent kinase 2
Multimeric state:
hetero dimer
Accessible surface area:
24136.75 Å2
Buried surface area:
3472.31 Å2
Dissociation area:
1,736.16
Å2
Dissociation energy (ΔGdiss):
13.84
kcal/mol
Dissociation entropy (TΔSdiss):
13.22
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-150314
Assembly Name:
Cyclin-A2 and Cyclin-dependent kinase 2
Multimeric state:
hetero dimer
Accessible surface area:
24090.73 Å2
Buried surface area:
3605.89 Å2
Dissociation area:
1,802.94
Å2
Dissociation energy (ΔGdiss):
16.26
kcal/mol
Dissociation entropy (TΔSdiss):
13.23
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-150314
Macromolecules
Chains: A, C
Length: 302 amino acids
Theoretical weight: 34.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Protein kinase domain
InterPro:
Length: 302 amino acids
Theoretical weight: 34.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P24941 (Residues: 1-298; Coverage: 100%)
Pfam: Protein kinase domain
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Protein kinase, ATP binding site
- Serine/threonine-protein kinase, active site
Chains: B, D
Length: 268 amino acids
Theoretical weight: 30.82 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 268 amino acids
Theoretical weight: 30.82 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P30274 (Residues: 170-430; Coverage: 61%)
Pfam:
InterPro:
- Cyclin A/B-like
- Cyclin-like superfamily
- Cyclin
- Cyclin, N-terminal
- Cyclin-like domain
- Cyclin, C-terminal domain
