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Structure of the mouse TRPC4 ion channel

Electron Microscopy
3.28Å resolution
PDB entry 6jzo coloured by chain, front view.
PDB entry 6jzo coloured by chain, side view.
PDB entry 6jzo coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Short transient receptor potential channel 4
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Multimeric state: homo tetramer
Accessible surface area: 115130.28 Å2
Buried surface area: 46542.33 Å2
Dissociation area: 20,959.23 Å2
Dissociation energy (ΔGdiss): 286.99 kcal/mol
Dissociation entropy (TΔSdiss): 53.09 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-193029

Macromolecules

Short transient receptor potential channel 4
Chains: A, B, C, D
Length: 755 amino acids
Theoretical weight: 87.56 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9QUQ5 (Residues: 1-755; Coverage: 78%)
Gene names: Trpc4, Trrp4
Pfam:
InterPro:
Short transient receptor potential channel 4 in PDB entry 6jzo, assembly 1, front view.
Short transient receptor potential channel 4 in PDB entry 6jzo, assembly 1, side view.
Short transient receptor potential channel 4 in PDB entry 6jzo, assembly 1, top view.
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