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High resolution structure of FANCA C-terminal domain (CTD)

Electron Microscopy
3.46Å resolution
PDB entry 6lhu coloured by chain, front view.
PDB entry 6lhu coloured by chain, side view.
PDB entry 6lhu coloured by chain, top view.
Source organism: Xenopus laevis
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fanconi anaemia group A protein N-terminal domain-containing protein
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Multimeric state: homo dimer
Accessible surface area: 69660.3 Å2
Buried surface area: 5605.48 Å2
Dissociation area: 2,802.74 Å2
Dissociation energy (ΔGdiss): 8.26 kcal/mol
Dissociation entropy (TΔSdiss): 16.22 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-175781

Macromolecules

Fanconi anaemia group A protein N-terminal domain-containing protein
Chains: A, B
Length: 1437 amino acids
Theoretical weight: 163.01 KDa
Source organism: Xenopus laevis
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q4VT51 (Residues: 1-1422; Coverage: 100%)
Gene names: FANCA, fa1, faa, faca, fanca, fanca.L, fanch, xFA, xfanca
Pfam:
InterPro:
Fanconi anaemia group A protein N-terminal domain-containing protein in PDB entry 6lhu, assembly 1, front view.
Fanconi anaemia group A protein N-terminal domain-containing protein in PDB entry 6lhu, assembly 1, side view.
Fanconi anaemia group A protein N-terminal domain-containing protein in PDB entry 6lhu, assembly 1, top view.
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