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Structure of FANCA and FANCG Complex

Electron Microscopy
4.59Å resolution
PDB entry 6lhv coloured by chain, front view.
PDB entry 6lhv coloured by chain, side view.
PDB entry 6lhv coloured by chain, top view.
Source organism: Xenopus laevis
Assembly composition:
hetero trimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Fanconi anemia complementation group a and Fanconi anemia complementation group g
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Multimeric state: hetero trimer
Accessible surface area: 104665.64 Å2
Buried surface area: 2286.54 Å2
Dissociation area: 87.52 Å2
Dissociation energy (ΔGdiss): -11.65 kcal/mol
Dissociation entropy (TΔSdiss): 13.69 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-167018

Macromolecules

Fanconi anemia complementation group G
Chain: C
Length: 400 amino acids
Theoretical weight: 34.06 KDa
Source organism: Xenopus laevis
Expression system: Trichoplusia ni
Fanconi anemia complementation group G in PDB entry 6lhv, assembly 1, front view.
Fanconi anemia complementation group G in PDB entry 6lhv, assembly 1, side view.
Fanconi anemia complementation group G in PDB entry 6lhv, assembly 1, top view.
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Fanconi anemia complementation group A
Chains: A, B
Length: 800 amino acids
Theoretical weight: 68.1 KDa
Source organism: Xenopus laevis
Expression system: Trichoplusia ni
Fanconi anemia complementation group A in PDB entry 6lhv, assembly 1, front view.
Fanconi anemia complementation group A in PDB entry 6lhv, assembly 1, side view.
Fanconi anemia complementation group A in PDB entry 6lhv, assembly 1, top view.
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