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Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form

Source organism: Macaca mulatta
Biochemical function: transmembrane signaling receptor activity
Biological process: immune response
Cellular component: membrane

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF13855
Domain description: Leucine rich repeat
Occurring in:
  1. TIR domain-containing protein
The deposited structure of PDB entry 6lw1 contains 8 copies of Pfam domain PF13855 (Leucine rich repeat) in TIR domain-containing protein. Showing 4 copies in chain A.

InterPro InterPro annotations
IPR003591
Domain description: Leucine-rich repeat, typical subtype
Occurring in:
  1. TIR domain-containing protein
IPR017241
Domain description: Toll-like receptor
Occurring in:
  1. TIR domain-containing protein
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. TIR domain-containing protein
IPR000483
Domain description: Cysteine-rich flanking region, C-terminal
Occurring in:
  1. TIR domain-containing protein
IPR026906
Domain description: BspA-type LRR region
Occurring in:
  1. TIR domain-containing protein
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. TIR domain-containing protein

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