Function and Biology Details
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Endonuclease 8-like 1 and DNA (preferred)
PDBe Complex ID:
PDB-CPX-120246 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):
Endonuclease 8-like 1
Molecule details ›
Chains: A, D, G
Length: 295 amino acids
Theoretical weight: 33.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 295 amino acids
Theoretical weight: 33.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q96FI4 (Residues: 1-295; Coverage: 76%)
Sequence domains:
