Function and Biology Details
Reactions catalysed:
(1a) L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero decamer (preferred)
PDBe Complex ID:
PDB-CPX-167173 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Cysteine desulfurase
Molecule details ›
Chains: A, E
Length: 403 amino acids
Theoretical weight: 44.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains: Aminotransferase class-V
Length: 403 amino acids
Theoretical weight: 44.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical:
Q9Y697 (Residues: 55-457; Coverage: 88%)
Sequence domains: Aminotransferase class-V
LYR motif-containing protein 4
Molecule details ›
Chains: B, F
Length: 92 amino acids
Theoretical weight: 10.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains: Complex 1 protein (LYR family)
Length: 92 amino acids
Theoretical weight: 10.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical: Q9HD34 (Residues: 1-91; Coverage: 100%)
Sequence domains: Complex 1 protein (LYR family)
Iron-sulfur cluster assembly enzyme ISCU
Frataxin mature form
