Structure analysis

In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (TLP_RNA)

Electron Microscopy
5.2Å resolution
Assembly composition:
hetero undecamer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero undecamer
Accessible surface area: 386707.06 Å2
Buried surface area: 69878.7 Å2
Dissociation area: 6,332.83 Å2
Dissociation energy (ΔGdiss): 18.87 kcal/mol
Dissociation entropy (TΔSdiss): 19.81 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-109838

Macromolecules

Chains: A, B, C, D, E, F, G, H, I, J
Length: 887 amino acids
Theoretical weight: 103.43 KDa
Source organism: Simian rotavirus A strain RRV
UniProt:
  • Canonical: B3F2X3 (Residues: 1-887; Coverage: 100%)
Pfam: Rotavirus VP2 protein
InterPro: Rotavirus VP2

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