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HUMAN IGG1 FC FRAGMENT, C239 INSERTION MUTANT

X-ray diffraction
2.31Å resolution
PDB entry 6p6d coloured by chain, front view.
PDB entry 6p6d coloured by chain, side view.
PDB entry 6p6d coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-heavy chain
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Multimeric state: homo dimer
Accessible surface area: 23133.06 Å2
Buried surface area: 7250.88 Å2
Dissociation area: 1,224.11 Å2
Dissociation energy (ΔGdiss): 3.41 kcal/mol
Dissociation entropy (TΔSdiss): 13.39 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-534181

Macromolecules

Immunoglobulin gamma-1 heavy chain
Chains: A, B
Length: 228 amino acids
Theoretical weight: 25.72 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DOX5 (Residues: 223-241, 242-449; Coverage: 51%)
Pfam: Immunoglobulin C1-set domain
InterPro:
Immunoglobulin gamma-1 heavy chain in PDB entry 6p6d, assembly 1, front view.
Immunoglobulin gamma-1 heavy chain in PDB entry 6p6d, assembly 1, side view.
Immunoglobulin gamma-1 heavy chain in PDB entry 6p6d, assembly 1, top view.
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