Assemblies
Multimeric state:
hetero trimer
Accessible surface area:
25971.29 Å2
Buried surface area:
5943.13 Å2
Dissociation area:
1,850.56
Å2
Dissociation energy (ΔGdiss):
22.99
kcal/mol
Dissociation entropy (TΔSdiss):
13.33
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-145930
Macromolecules
Chain: A
Length: 249 amino acids
Theoretical weight: 28.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam:
InterPro:
Length: 249 amino acids
Theoretical weight: 28.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P24385 (Residues: 19-267; Coverage: 84%)
Pfam:
InterPro:
Chain: B
Length: 302 amino acids
Theoretical weight: 33.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt: Gene name: CDK4
Pfam: Protein kinase domain
InterPro:
Length: 302 amino acids
Theoretical weight: 33.95 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt: Gene name: CDK4
Pfam: Protein kinase domain
InterPro:
Chain: C
Length: 80 amino acids
Theoretical weight: 9.09 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Cyclin-dependent kinase inhibitor
InterPro:
Length: 80 amino acids
Theoretical weight: 9.09 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P38936 (Residues: 9-85; Coverage: 47%)
Pfam: Cyclin-dependent kinase inhibitor
InterPro: