6pd9 › Citations

Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.

Priebbenow DL, Leaver DJ, Nguyen N, Cleary B, Lagiakos HR, Sanchez J, Xue L, Huang F, Sun Y, Mujumdar P, Mudududdla R, Varghese S, Teguh S, Charman SA, White KL, Shackleford DM, Katneni K, Cuellar M, Strasser JM, Dahlin JL, Walters MA, Street IP, Monahan BJ, Jarman KE, Jousset Sabroux H, Falk H, Chung MC, Hermans SJ, Downer NL, Parker MW, Voss AK, Thomas T, Baell JB
J Med Chem 63 4655-4684 (2020)
Related entries: 6owh, 6owi, 6pd8, 6pda, 6pdb, 6pdc, 6pdd, 6pde, 6pdf, 6pdg

Cited: 2 times
EuropePMC logo PMID: 32118427

Abstract

A high-throughput screen designed to discover new inhibitors of histone acetyltransferase KAT6A uncovered CTX-0124143 (

Reviews citing this publication (1)

  1. Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials. Patton EE, Zon LI, Langenau DM. Nat Rev Drug Discov 20 611-628 (2021)

Articles citing this publication (1)

  1. First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8. Fiorentino F, Sementilli S, Menna M, Turrisi F, Tomassi S, Pellegrini FR, Iuzzolino A, D'Acunzo F, Feoli A, Wapenaar H, Taraglio S, Fraschetti C, Del Bufalo D, Sbardella G, Dekker FJ, Paiardini A, Trisciuoglio D, Mai A, Rotili D. J Med Chem 66 6591-6616 (2023)


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