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CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, desensitized state

Electron Microscopy
3Å resolution
PDB entry 6pls coloured by chain, front view.
PDB entry 6pls coloured by chain, side view.
PDB entry 6pls coloured by chain, top view.
Source organism: Danio rerio
Assembly composition:
homo pentamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Glycine receptor subunit alphaZ1
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Multimeric state: homo pentamer
Accessible surface area: 77942.35 Å2
Buried surface area: 45989.11 Å2
Dissociation area: 13,628.64 Å2
Dissociation energy (ΔGdiss): 64.51 kcal/mol
Dissociation entropy (TΔSdiss): 62.31 kcal/mol
Symmetry number: 5
PDBe Complex ID: PDB-CPX-131665

Macromolecules

Glycine receptor subunit alphaZ1
Chains: A, B, C, D, E
Length: 458 amino acids
Theoretical weight: 52.54 KDa
Source organism: Danio rerio
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O93430 (Residues: 1-444; Coverage: 100%)
Gene name: glra1
Pfam:
InterPro:
Glycine receptor subunit alphaZ1 in PDB entry 6pls, assembly 1, front view.
Glycine receptor subunit alphaZ1 in PDB entry 6pls, assembly 1, side view.
Glycine receptor subunit alphaZ1 in PDB entry 6pls, assembly 1, top view.
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