Structure analysis

Kaposi's sarcoma-associated herpesvirus (KSHV), C12 portal dodecamer structure

Electron Microscopy
4.7Å resolution
Assembly composition:
homo dodecamer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dodecamer
Accessible surface area: 218348.01 Å2
Buried surface area: 98527.8 Å2
Dissociation area: 49,263.9 Å2
Dissociation energy (ΔGdiss): 479.69 kcal/mol
Dissociation entropy (TΔSdiss): 180.85 kcal/mol
Symmetry number: 12
PDBe Complex ID: PDB-CPX-123580

Macromolecules

Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 605 amino acids
Theoretical weight: 68.09 KDa
Source organism: Human herpesvirus 8 strain GK18
UniProt:
  • Canonical: F5HGK9 (Residues: 1-605; Coverage: 100%)
Gene name: ORF43
Pfam: Herpesvirus UL6 like
InterPro: Herpesvirus portal protein

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