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E. coli ATP Synthase State 1e

Electron Microscopy
3.3Å resolution
PDB entry 6pqv coloured by chain, front view.
PDB entry 6pqv coloured by chain, side view.
PDB entry 6pqv coloured by chain, top view.
Source organism: Escherichia coli
Assembly composition:
hetero 22-mer (preferred)
Entry contents: 8 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: ATP synthase complex
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Multimeric state: hetero 22-mer
Accessible surface area: 174005.7 Å2
Buried surface area: 99093.93 Å2
Dissociation area: 4,443.11 Å2
Dissociation energy (ΔGdiss): 37.52 kcal/mol
Dissociation entropy (TΔSdiss): 16.42 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-141304
Complex Portal ID: CPX-4022

Macromolecules

ATP synthase subunit delta
Chain: W
Length: 177 amino acids
Theoretical weight: 19.29 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABA4 (Residues: null; Coverage: null%)
Gene names: JW3713, atpH, b3735, papE, uncH
Pfam: ATP synthase delta (OSCP) subunit
InterPro:
ATP synthase subunit delta in PDB entry 6pqv, assembly 1, front view.
ATP synthase subunit delta in PDB entry 6pqv, assembly 1, side view.
ATP synthase subunit delta in PDB entry 6pqv, assembly 1, top view.
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ATP synthase subunit alpha
Chains: A, B, C
Length: 513 amino acids
Theoretical weight: 55.28 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABB0 (Residues: null; Coverage: null%)
Gene names: JW3712, atpA, b3734, papA, uncA
Pfam:
InterPro:
ATP synthase subunit alpha in PDB entry 6pqv, assembly 1, front view.
ATP synthase subunit alpha in PDB entry 6pqv, assembly 1, side view.
ATP synthase subunit alpha in PDB entry 6pqv, assembly 1, top view.
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ATP synthase subunit b
Chains: X, Y
Length: 156 amino acids
Theoretical weight: 17.26 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABA0 (Residues: null; Coverage: null%)
Gene names: JW3714, atpF, b3736, papF, uncF
Pfam: ATP synthase B/B' CF(0)
InterPro:
ATP synthase subunit b in PDB entry 6pqv, assembly 1, front view.
ATP synthase subunit b in PDB entry 6pqv, assembly 1, side view.
ATP synthase subunit b in PDB entry 6pqv, assembly 1, top view.
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ATP synthase epsilon chain
Chain: H
Length: 139 amino acids
Theoretical weight: 15.09 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A6E6 (Residues: null; Coverage: null%)
Gene names: JW3709, atpC, b3731, papG, uncC
Pfam:
InterPro:
ATP synthase epsilon chain in PDB entry 6pqv, assembly 1, front view.
ATP synthase epsilon chain in PDB entry 6pqv, assembly 1, side view.
ATP synthase epsilon chain in PDB entry 6pqv, assembly 1, top view.
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ATP synthase gamma chain
Chain: G
Length: 287 amino acids
Theoretical weight: 31.54 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABA6 (Residues: null; Coverage: null%)
Gene names: JW3711, atpG, b3733, papC, uncG
Pfam: ATP synthase
InterPro:
ATP synthase gamma chain in PDB entry 6pqv, assembly 1, front view.
ATP synthase gamma chain in PDB entry 6pqv, assembly 1, side view.
ATP synthase gamma chain in PDB entry 6pqv, assembly 1, top view.
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ATP synthase subunit beta
Chains: D, E, F
Length: 471 amino acids
Theoretical weight: 51.66 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0ABB4 (Residues: null; Coverage: null%)
Gene names: JW3710, atpD, b3732, papB, uncD
Pfam:
InterPro:
ATP synthase subunit beta in PDB entry 6pqv, assembly 1, front view.
ATP synthase subunit beta in PDB entry 6pqv, assembly 1, side view.
ATP synthase subunit beta in PDB entry 6pqv, assembly 1, top view.
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ATP synthase subunit c
Chains: I, J, L, M, N, O, P, Q, R, S
Length: 79 amino acids
Theoretical weight: 8.26 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P68699 (Residues: null; Coverage: null%)
Gene names: JW3715, atpE, b3737, papH, uncE
Pfam: ATP synthase subunit C
InterPro:
ATP synthase subunit c in PDB entry 6pqv, assembly 1, front view.
ATP synthase subunit c in PDB entry 6pqv, assembly 1, side view.
ATP synthase subunit c in PDB entry 6pqv, assembly 1, top view.
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ATP synthase subunit a
Chain: a
Length: 271 amino acids
Theoretical weight: 30.32 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AB98 (Residues: null; Coverage: null%)
Gene names: JW3716, atpB, b3738, papD, uncB
Pfam: ATP synthase A chain
InterPro:
ATP synthase subunit a in PDB entry 6pqv, assembly 1, front view.
ATP synthase subunit a in PDB entry 6pqv, assembly 1, side view.
ATP synthase subunit a in PDB entry 6pqv, assembly 1, top view.
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