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Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2

Electron Microscopy
3.3Å resolution
PDB entry 6rfq coloured by chain, front view.
PDB entry 6rfq coloured by chain, side view.
PDB entry 6rfq coloured by chain, top view.
Source organism: Yarrowia lipolytica
Assembly composition:
hetero 41-mer (preferred)
Entry contents: 41 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero 41-mer
Accessible surface area: 257149.09 Å2
Buried surface area: 271052.47 Å2
Dissociation area: 1,101.52 Å2
Dissociation energy (ΔGdiss): -0.3 kcal/mol
Dissociation entropy (TΔSdiss): 11.82 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-103385

Macromolecules

YALI0D05467p
Chain: A
Length: 728 amino acids
Theoretical weight: 79.09 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z6F1 (Residues: 1-728; Coverage: 100%)
Gene name: YALI0_D05467g
Pfam:
InterPro:
YALI0D05467p in PDB entry 6rfq, assembly 1, front view.
YALI0D05467p in PDB entry 6rfq, assembly 1, side view.
YALI0D05467p in PDB entry 6rfq, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Chain: B
Length: 488 amino acids
Theoretical weight: 53.83 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z660 (Residues: 1-488; Coverage: 100%)
Gene name: YALI0_B20372g
Pfam:
InterPro:
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 6rfq, assembly 1, front view.
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 6rfq, assembly 1, side view.
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial in PDB entry 6rfq, assembly 1, top view.
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NADH-quinone oxidoreductase subunit D domain-containing protein
Chain: C
Length: 466 amino acids
Theoretical weight: 52.49 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z626 (Residues: 1-466; Coverage: 100%)
Gene name: YALI0_F17248g
Pfam: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
InterPro:
NADH-quinone oxidoreductase subunit D domain-containing protein in PDB entry 6rfq, assembly 1, front view.
NADH-quinone oxidoreductase subunit D domain-containing protein in PDB entry 6rfq, assembly 1, side view.
NADH-quinone oxidoreductase subunit D domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Chain: D
Length: 87 amino acids
Theoretical weight: 9.81 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5FVD3 (Residues: 1-87; Coverage: 100%)
Gene name: YALI0_C21789g
Pfam: NADH-ubiquinone oxidoreductase MWFE subunit
InterPro: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 6rfq, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 6rfq, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 in PDB entry 6rfq, assembly 1, top view.
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NAD-dependent epimerase/dehydratase domain-containing protein
Chain: E
Length: 375 amino acids
Theoretical weight: 42.77 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C7X4 (Residues: 1-375; Coverage: 100%)
Gene name: YALI0_D24585g
Pfam: NAD dependent epimerase/dehydratase family
InterPro:
NAD-dependent epimerase/dehydratase domain-containing protein in PDB entry 6rfq, assembly 1, front view.
NAD-dependent epimerase/dehydratase domain-containing protein in PDB entry 6rfq, assembly 1, side view.
NAD-dependent epimerase/dehydratase domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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ETC complex I subunit conserved region-domain-containing protein
Chain: F
Length: 144 amino acids
Theoretical weight: 16.66 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C4W9 (Residues: 1-144; Coverage: 100%)
Gene name: YALI0_E23089g
Pfam: ETC complex I subunit conserved region
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
ETC complex I subunit conserved region-domain-containing protein in PDB entry 6rfq, assembly 1, front view.
ETC complex I subunit conserved region-domain-containing protein in PDB entry 6rfq, assembly 1, side view.
ETC complex I subunit conserved region-domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein
Chain: G
Length: 281 amino acids
Theoretical weight: 32.39 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z6D7 (Residues: 1-281; Coverage: 100%)
Gene name: YALI0_F02123g
Pfam: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
InterPro:
NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein in PDB entry 6rfq, assembly 1, front view.
NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein in PDB entry 6rfq, assembly 1, side view.
NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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YALI0D00737p
Chain: H
Length: 243 amino acids
Theoretical weight: 27.25 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z6C0 (Residues: 1-243; Coverage: 100%)
Gene name: YALI0_D00737g
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
InterPro:
YALI0D00737p in PDB entry 6rfq, assembly 1, front view.
YALI0D00737p in PDB entry 6rfq, assembly 1, side view.
YALI0D00737p in PDB entry 6rfq, assembly 1, top view.
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4Fe-4S ferredoxin-type domain-containing protein
Chain: I
Length: 229 amino acids
Theoretical weight: 25.68 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z619 (Residues: 1-229; Coverage: 100%)
Gene name: YALI0_F00924g
Pfam: 4Fe-4S dicluster domain
InterPro:
4Fe-4S ferredoxin-type domain-containing protein in PDB entry 6rfq, assembly 1, front view.
4Fe-4S ferredoxin-type domain-containing protein in PDB entry 6rfq, assembly 1, side view.
4Fe-4S ferredoxin-type domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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YALI0E11891p
Chain: J
Length: 198 amino acids
Theoretical weight: 20.85 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C674 (Residues: 1-198; Coverage: 100%)
Gene name: YALI0_E11891g
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
YALI0E11891p in PDB entry 6rfq, assembly 1, front view.
YALI0E11891p in PDB entry 6rfq, assembly 1, side view.
YALI0E11891p in PDB entry 6rfq, assembly 1, top view.
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NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein
Chain: K
Length: 210 amino acids
Theoretical weight: 23.46 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C2Q1 (Residues: 1-173; Coverage: 80%)
Gene name: YALI0_F06050g
Pfam: NADH ubiquinone oxidoreductase, 20 Kd subunit
InterPro:
NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein in PDB entry 6rfq, assembly 1, front view.
NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein in PDB entry 6rfq, assembly 1, side view.
NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 4L
Chain: L
Length: 89 amino acids
Theoretical weight: 9.82 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6D4 (Residues: 1-89; Coverage: 100%)
Gene name: ND4L
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
InterPro:
NADH-ubiquinone oxidoreductase chain 4L in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 4L in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 4L in PDB entry 6rfq, assembly 1, top view.
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Acyl carrier protein
Chain: O
Length: 109 amino acids
Theoretical weight: 12.05 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C926 (Residues: 1-109; Coverage: 100%)
Gene name: YALI0_D14850g
Pfam: Phosphopantetheine attachment site
InterPro:
Acyl carrier protein in PDB entry 6rfq, assembly 1, front view.
Acyl carrier protein in PDB entry 6rfq, assembly 1, side view.
Acyl carrier protein in PDB entry 6rfq, assembly 1, top view.
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Complex 1 LYR protein domain-containing protein
Chain: P
Length: 124 amino acids
Theoretical weight: 14.78 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6CI60 (Residues: 1-124; Coverage: 100%)
Gene name: YALI0_A01419g
Pfam: Complex1_LYR-like
InterPro:
Complex 1 LYR protein domain-containing protein in PDB entry 6rfq, assembly 1, front view.
Complex 1 LYR protein domain-containing protein in PDB entry 6rfq, assembly 1, side view.
Complex 1 LYR protein domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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Acyl carrier protein
Chain: Q
Length: 132 amino acids
Theoretical weight: 14.44 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C7X2 (Residues: 1-132; Coverage: 100%)
Gene name: YALI0_D24629g
Pfam: Phosphopantetheine attachment site
InterPro:
Acyl carrier protein in PDB entry 6rfq, assembly 1, front view.
Acyl carrier protein in PDB entry 6rfq, assembly 1, side view.
Acyl carrier protein in PDB entry 6rfq, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Chain: R
Length: 109 amino acids
Theoretical weight: 12.9 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C9Z1 (Residues: 1-109; Coverage: 100%)
Gene name: YALI0_D07216g
InterPro:
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 6rfq, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 6rfq, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 in PDB entry 6rfq, assembly 1, top view.
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NUWM protein
Chain: S
Length: 249 amino acids
Theoretical weight: 28.48 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: F2Z673 (Residues: 1-249; Coverage: 100%)
Gene name: YALI0_E29095g
NUWM protein in PDB entry 6rfq, assembly 1, front view.
NUWM protein in PDB entry 6rfq, assembly 1, side view.
NUWM protein in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase
Chain: U
Length: 172 amino acids
Theoretical weight: 19.36 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6CGB4 (Residues: 1-172; Coverage: 100%)
Gene name: YALI0_A20680g
Pfam: CHCH domain
InterPro:
NADH-ubiquinone oxidoreductase in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase in PDB entry 6rfq, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
Chain: W
Length: 123 amino acids
Theoretical weight: 14.11 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5FVF8 (Residues: 1-123; Coverage: 100%)
Gene name: YALI0_E28930g
Pfam: GRIM-19 protein
InterPro: GRIM-19
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 6rfq, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 6rfq, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase 21 kDa subunit
Chain: X
Length: 169 amino acids
Theoretical weight: 18.59 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C4A6 (Residues: 1-169; Coverage: 100%)
Gene name: YALI0_E28424g
Pfam:
InterPro:
NADH-ubiquinone oxidoreductase 21 kDa subunit in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase 21 kDa subunit in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase 21 kDa subunit in PDB entry 6rfq, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
Chain: Y
Length: 161 amino acids
Theoretical weight: 18.66 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6CEK9 (Residues: 1-161; Coverage: 100%)
Gene name: YALI0_B14861g
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
InterPro:
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 6rfq, assembly 1, front view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 6rfq, assembly 1, side view.
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase 21.3 kDa subunit
Chain: Z
Length: 182 amino acids
Theoretical weight: 19.77 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6CI10 (Residues: 1-182; Coverage: 100%)
Gene name: YALI0_A02651g
InterPro: NADH-ubiquinone oxidoreductase 21.3 kDa subunit
NADH-ubiquinone oxidoreductase 21.3 kDa subunit in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase 21.3 kDa subunit in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase 21.3 kDa subunit in PDB entry 6rfq, assembly 1, top view.
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YALI0D04939p
Chain: a
Length: 149 amino acids
Theoretical weight: 17.33 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6CA88 (Residues: 1-149; Coverage: 100%)
Gene name: YALI0_D04939g
Pfam: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8
YALI0D04939p in PDB entry 6rfq, assembly 1, front view.
YALI0D04939p in PDB entry 6rfq, assembly 1, side view.
YALI0D04939p in PDB entry 6rfq, assembly 1, top view.
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Subunit NEBM of NADH:Ubiquinone Oxidoreductase (Complex I)
Chain: b
Length: 74 amino acids
Theoretical weight: 8.06 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: A0A1D8NGI5 (Residues: 1-74; Coverage: 100%)
Gene name: YALI1_E00527g
Subunit NEBM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, front view.
Subunit NEBM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, side view.
Subunit NEBM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase B12 subunit family-domain-containing protein
Chain: c
Length: 60 amino acids
Theoretical weight: 6.95 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5FVE5 (Residues: 1-60; Coverage: 100%)
Gene name: YALI0_D10274g
Pfam: NADH-ubiquinone oxidoreductase B12 subunit family
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
NADH-ubiquinone oxidoreductase B12 subunit family-domain-containing protein in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase B12 subunit family-domain-containing protein in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase B12 subunit family-domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase 12 kDa subunit
Chain: d
Length: 92 amino acids
Theoretical weight: 11.04 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5RSK3 (Residues: 1-92; Coverage: 100%)
Gene name: YALI0_A17946g
Pfam: NADH-ubiquinone oxidoreductase subunit 10
InterPro:
NADH-ubiquinone oxidoreductase 12 kDa subunit in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase 12 kDa subunit in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase 12 kDa subunit in PDB entry 6rfq, assembly 1, top view.
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Subunit NUVM of NADH:Ubiquinone Oxidoreductase (Complex I)
Chain: e
Length: 67 amino acids
Theoretical weight: 7.81 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: A0A1D8NFX6 (Residues: 1-67; Coverage: 100%)
Gene names: B0I71DRAFT_129560, YALI1_D30003g
Subunit NUVM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, front view.
Subunit NUVM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, side view.
Subunit NUVM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, top view.
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Ribosomal protein/NADH dehydrogenase domain-containing protein
Chain: f
Length: 87 amino acids
Theoretical weight: 9.62 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6CD73 (Residues: 1-87; Coverage: 100%)
Gene name: YALI0_C03201g
Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
InterPro:
Ribosomal protein/NADH dehydrogenase domain-containing protein in PDB entry 6rfq, assembly 1, front view.
Ribosomal protein/NADH dehydrogenase domain-containing protein in PDB entry 6rfq, assembly 1, side view.
Ribosomal protein/NADH dehydrogenase domain-containing protein in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase 9.5 kDa subunit
Chain: g
Length: 78 amino acids
Theoretical weight: 8.92 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5FVF3 (Residues: 1-78; Coverage: 100%)
Gene name: YALI0_E23749g
InterPro: NADH-ubiquinone oxidoreductase 9.5kDa subunit
NADH-ubiquinone oxidoreductase 9.5 kDa subunit in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase 9.5 kDa subunit in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase 9.5 kDa subunit in PDB entry 6rfq, assembly 1, top view.
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Subunit N7BM of NADH:Ubiquinone Oxidoreductase (Complex I)
Chain: i
Length: 90 amino acids
Theoretical weight: 9.79 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: A0A1H6Q311 (Residues: 1-90; Coverage: 100%)
Gene names: B0I71DRAFT_133979, YALI1_D22691g
Subunit N7BM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, front view.
Subunit N7BM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, side view.
Subunit N7BM of NADH:Ubiquinone Oxidoreductase (Complex I) in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase B15 subunit
Chain: j
Length: 93 amino acids
Theoretical weight: 10.49 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5RSK9 (Residues: 1-93; Coverage: 100%)
Gene name: YALI0_F06061g
NADH-ubiquinone oxidoreductase B15 subunit in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase B15 subunit in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase B15 subunit in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase assembly factor N7BML
Chain: k
Length: 237 amino acids
Theoretical weight: 27.65 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C7L6 (Residues: 1-237; Coverage: 100%)
Gene names: N7BML, YALI0D27082g
Pfam: NADH ubiquinone oxidoreductase subunit NDUFA12
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
NADH-ubiquinone oxidoreductase assembly factor N7BML in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase assembly factor N7BML in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase assembly factor N7BML in PDB entry 6rfq, assembly 1, top view.
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YALI0F14003p
Chain: n
Length: 120 amino acids
Theoretical weight: 13.52 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q6C1R9 (Residues: 20-139; Coverage: 86%)
Gene name: YALI0_F14003g
YALI0F14003p in PDB entry 6rfq, assembly 1, front view.
YALI0F14003p in PDB entry 6rfq, assembly 1, side view.
YALI0F14003p in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 1
Chain: 1
Length: 341 amino acids
Theoretical weight: 38.36 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6E8 (Residues: 1-341; Coverage: 100%)
Gene name: ND1
Pfam: NADH dehydrogenase
InterPro:
NADH-ubiquinone oxidoreductase chain 1 in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 1 in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 1 in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 2
Chain: 2
Length: 469 amino acids
Theoretical weight: 53.35 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6C8 (Residues: 1-469; Coverage: 100%)
Gene name: ND2
Pfam: Proton-conducting membrane transporter
InterPro: NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
NADH-ubiquinone oxidoreductase chain 2 in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 2 in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 2 in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 3
Chain: 3
Length: 128 amino acids
Theoretical weight: 14.48 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6C7 (Residues: 1-128; Coverage: 100%)
Gene name: ND3
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
InterPro:
NADH-ubiquinone oxidoreductase chain 3 in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 3 in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 3 in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 4
Chain: 4
Length: 486 amino acids
Theoretical weight: 54.51 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6D6 (Residues: 1-486; Coverage: 100%)
Gene name: ND4
Pfam: Proton-conducting membrane transporter
InterPro:
NADH-ubiquinone oxidoreductase chain 4 in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 4 in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 4 in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 5
Chain: 5
Length: 655 amino acids
Theoretical weight: 73.74 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6D3 (Residues: 1-655; Coverage: 100%)
Gene name: ND5
Pfam:
InterPro:
NADH-ubiquinone oxidoreductase chain 5 in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 5 in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 5 in PDB entry 6rfq, assembly 1, top view.
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NADH-ubiquinone oxidoreductase chain 6
Chain: 6
Length: 185 amino acids
Theoretical weight: 20.77 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: Q9B6E9 (Residues: 1-185; Coverage: 100%)
Gene name: ND6
Pfam: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
InterPro:
NADH-ubiquinone oxidoreductase chain 6 in PDB entry 6rfq, assembly 1, front view.
NADH-ubiquinone oxidoreductase chain 6 in PDB entry 6rfq, assembly 1, side view.
NADH-ubiquinone oxidoreductase chain 6 in PDB entry 6rfq, assembly 1, top view.
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NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Chain: 8
Length: 99 amino acids
Theoretical weight: 11.22 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5FVG1 (Residues: 1-99; Coverage: 100%)
Gene name: YALI0_E31766g
Pfam: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
InterPro: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 6rfq, assembly 1, front view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 6rfq, assembly 1, side view.
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 in PDB entry 6rfq, assembly 1, top view.
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YALI0F18359p
Chain: 9
Length: 89 amino acids
Theoretical weight: 10.04 KDa
Source organism: Yarrowia lipolytica
UniProt:
  • Canonical: B5RSL7 (Residues: 1-89; Coverage: 100%)
Gene name: YALI0_F18359g
Pfam: NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
InterPro: NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5
YALI0F18359p in PDB entry 6rfq, assembly 1, front view.
YALI0F18359p in PDB entry 6rfq, assembly 1, side view.
YALI0F18359p in PDB entry 6rfq, assembly 1, top view.
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