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CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(3,5)P2

Source organism: Homo sapiens
Biochemical function: calcium ion binding
Biological process: not assigned
Cellular component: membrane

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GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF08016
Domain description: Polycystin cation channel
Occurring in:
  1. Polycystin-2
The deposited structure of PDB entry 6t9o contains 4 copies of Pfam domain PF08016 (Polycystin cation channel) in Polycystin-2. Showing 1 copy in chain A.

PF00520
Domain description: Ion transport protein
Occurring in:
  1. Polycystin-2
The deposited structure of PDB entry 6t9o contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Polycystin-2. Showing 1 copy in chain A.

PF20519
Domain description: Polycystin domain
Occurring in:
  1. Polycystin-2
The deposited structure of PDB entry 6t9o contains 4 copies of Pfam domain PF20519 (Polycystin domain) in Polycystin-2. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003915
Domain description: Polycystic kidney disease type 2 protein
Occurring in:
  1. Polycystin-2
IPR027359
Domain description: Voltage-dependent channel domain superfamily
Occurring in:
  1. Polycystin-2
IPR013122
Domain description: Polycystin cation channel, PKD1/PKD2
Occurring in:
  1. Polycystin-2
IPR046791
Domain description: Polycystin domain
Occurring in:
  1. Polycystin-2

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