Articles - 6ujb mentioned but not cited (1)
- Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β. Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. Cell 180 490-501.e16 (2020)
Reviews citing this publication (27)
- Transforming growth factor-β1 in regulatory T cell biology. Moreau JM, Velegraki M, Bolyard C, Rosenblum MD, Li Z. Sci Immunol 7 eabi4613 (2022)
- Transforming Growth Factor-β: A Multifunctional Regulator of Cancer Immunity. Xue VW, Chung JY, Córdoba CAG, Cheung AH, Kang W, Lam EW, Leung KT, To KF, Lan HY, Tang PM. Cancers (Basel) 12 E3099 (2020)
- The Roles of TGF-β Signaling in Cerebrovascular Diseases. Zhang Y, Yang X. Front Cell Dev Biol 8 567682 (2020)
- αvβ8 integrin adhesion and signaling pathways in development, physiology and disease. McCarty JH. J Cell Sci 133 jcs239434 (2020)
- Overcoming TGFβ-mediated immune evasion in cancer. Tauriello DVF, Sancho E, Batlle E. Nat Rev Cancer 22 25-44 (2022)
- TGF-β signaling in health and disease. Massagué J, Sheppard D. Cell 186 4007-4037 (2023)
- The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney. Higgins CE, Tang J, Higgins SP, Gifford CC, Mian BM, Jones DM, Zhang W, Costello A, Conti DJ, Samarakoon R, Higgins PJ. Front Cell Dev Biol 9 678524 (2021)
- The pre-metastatic niche in lymph nodes: formation and characteristics. Gillot L, Baudin L, Rouaud L, Kridelka F, Noël A. Cell Mol Life Sci 78 5987-6002 (2021)
- TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective. Nixon BG, Gao S, Wang X, Li MO. Nat Rev Immunol (2022)
- Targeting immunosuppression by TGF-β1 for cancer immunotherapy. de Streel G, Lucas S. Biochem Pharmacol 192 114697 (2021)
- Cryo-electron Microscopic Analysis of Single-Pass Transmembrane Receptors. Cai K, Zhang X, Bai XC. Chem Rev 122 13952-13988 (2022)
- Fibrosis: from mechanisms to medicines. Henderson NC, Rieder F, Wynn TA. Nature 587 555-566 (2020)
- Bispecific antibody targeting TGF-β and PD-L1 for synergistic cancer immunotherapy. Li T, Wang X, Niu M, Wang M, Zhou J, Wu K, Yi M. Front Immunol 14 1196970 (2023)
- Cell Adhesion Molecules in Plasticity and Metastasis. Smart JA, Oleksak JE, Hartsough EJ. Mol Cancer Res 19 25-37 (2021)
- Elastic Fibre Proteins in Elastogenesis and Wound Healing. Zhang X, Alanazi YF, Jowitt TA, Roseman AM, Baldock C. Int J Mol Sci 23 4087 (2022)
- Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy. Tan M, Ge Y, Wang X, Wang Y, Liu Y, He F, Teng H. Technol Cancer Res Treat 22 15330338231171463 (2023)
- Integrin, Exosome and Kidney Disease. Shen AR, Zhong X, Tang TT, Wang C, Jing J, Liu BC, Lv LL. Front Physiol 11 627800 (2020)
- It's Time to Shift the Paradigm: Translation and Clinical Application of Non-αvβ3 Integrin Targeting Radiopharmaceuticals. Kossatz S, Beer AJ, Notni J. Cancers (Basel) 13 5958 (2021)
- New insight into GARP striking role in cancer progression: application for cancer therapy. Lahimchi MR, Eslami M, Yousefi B. Med Oncol 40 33 (2022)
- New perspectives on the regulation of germinal center reaction via αvβ8- mediated activation of TGFβ. This S, Paidassi H. Front Immunol 13 942468 (2022)
- On the Value of In Vitro Cell Systems for Mechanobiology from the Perspective of Yes-Associated Protein/Transcriptional Co-Activator with a PDZ-Binding Motif and Focal Adhesion Kinase and Their Involvement in Wound Healing, Cancer, Aging, and Senescence. Steinberg T, Dieterle MP, Ramminger I, Klein C, Brossette J, Husari A, Tomakidi P. Int J Mol Sci 24 12677 (2023)
- Organization, dynamics and mechanoregulation of integrin-mediated cell-ECM adhesions. Kanchanawong P, Calderwood DA. Nat Rev Mol Cell Biol (2022)
- TGF-beta signal transduction: biology, function and therapy for diseases. Tie Y, Tang F, Peng D, Zhang Y, Shi H. Mol Biomed 3 45 (2022)
- Targeting TGF-β signal transduction for fibrosis and cancer therapy. Peng D, Fu M, Wang M, Wei Y, Wei X. Mol Cancer 21 104 (2022)
- Targeting integrin pathways: mechanisms and advances in therapy. Pang X, He X, Qiu Z, Zhang H, Xie R, Liu Z, Gu Y, Zhao N, Xiang Q, Cui Y. Signal Transduct Target Ther 8 1 (2023)
- The Multiple Faces of Integrin-ECM Interactions in Inflammatory Bowel Disease. Garlatti V, Lovisa S, Danese S, Vetrano S. Int J Mol Sci 22 10439 (2021)
- The role of pro-domains in human growth factors and cytokines. Ratcliff M, Zhou RX, Jermutus L, Hyvönen M. Biochem Soc Trans 49 1963-1973 (2021)
Articles citing this publication (37)
- Micellized Protein Transduction Domain-Bone Morphogenetic Protein-7 Efficiently Blocks Renal Fibrosis Via Inhibition of Transforming Growth Factor-Beta-Mediated Epithelial-Mesenchymal Transition. Kim S, Jeong CH, Song SH, Um JE, Kim HS, Yun JS, Han D, Cho ES, Nam BY, Yook JI, Ku M, Yang J, Kim MD, Kim NH, Yoo TH. Front Pharmacol 11 591275 (2020)
- EZH2 engages TGFβ signaling to promote breast cancer bone metastasis via integrin β1-FAK activation. Zhang L, Qu J, Qi Y, Duan Y, Huang YW, Zhou Z, Li P, Yao J, Huang B, Zhang S, Yu D. Nat Commun 13 2543 (2022)
- GARP-mediated active TGF-β1 induces bone marrow NK cell dysfunction in AML patients with early relapse post-allo-HSCT. Wang D, Sun Z, Zhu X, Zheng X, Zhou Y, Lu Y, Yan P, Wang H, Liu H, Jin J, Zhu H, Sun R, Wang Y, Fu B, Tian Z, Wei H. Blood 140 2788-2804 (2022)
- The parasite cytokine mimic Hp-TGM potently replicates the regulatory effects of TGF-β on murine CD4+ T cells. White MPJ, Smyth DJ, Cook L, Ziegler SF, Levings MK, Maizels RM. Immunol Cell Biol 99 848-864 (2021)
- Integrin-αV-mediated activation of TGF-β regulates anti-tumour CD8 T cell immunity and response to PD-1 blockade. Malenica I, Adam J, Corgnac S, Mezquita L, Auclin E, Damei I, Grynszpan L, Gros G, de Montpréville V, Planchard D, Théret N, Besse B, Mami-Chouaib F. Nat Commun 12 5209 (2021)
- A general chemical principle for creating closure-stabilizing integrin inhibitors. Lin FY, Li J, Xie Y, Zhu J, Huong Nguyen TT, Zhang Y, Zhu J, Springer TA. Cell 185 3533-3550.e27 (2022)
- Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS. Anderson JM, Li J, Springer TA. Mol Biol Cell 33 ar56 (2022)
- Structural insights into integrin α5β1 opening by fibronectin ligand. Schumacher S, Dedden D, Nunez RV, Matoba K, Takagi J, Biertümpfel C, Mizuno N. Sci Adv 7 eabe9716 (2021)
- Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation. Moreau JM, Dhariwala MO, Gouirand V, Boda DP, Boothby IC, Lowe MM, Cohen JN, Macon CE, Leech JM, Kalekar LA, Scharschmidt TC, Rosenblum MD. Sci Immunol 6 eabg2329 (2021)
- Structural mechanism of laminin recognition by integrin. Arimori T, Miyazaki N, Mihara E, Takizawa M, Taniguchi Y, Cabañas C, Sekiguchi K, Takagi J. Nat Commun 12 4012 (2021)
- Tgfβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration. Kaji DA, Howell KL, Balic Z, Hubmacher D, Huang AH. Elife 9 (2020)
- A tumor-specific mechanism of Treg enrichment mediated by the integrin αvβ8. Seed RI, Kobayashi K, Ito S, Takasaka N, Cormier A, Jespersen JM, Publicover J, Trilok S, Combes AJ, Chew NW, Chapman J, Krummel MF, Lou J, Marks J, Cheng Y, Baron JL, Nishimura SL. Sci Immunol 6 eabf0558 (2021)
- Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF. Decaris ML, Schaub JR, Chen C, Cha J, Lee GG, Rexhepaj M, Ho SS, Rao V, Marlow MM, Kotak P, Budi EH, Hooi L, Wu J, Fridlib M, Martin SP, Huang S, Chen M, Muñoz M, Hom TF, Wolters PJ, Desai TJ, Rock F, Leftheris K, Morgans DJ, Lepist EI, Andre P, Lefebvre EA, Turner SM. Respir Res 22 265 (2021)
- Enhancing the signal-to-noise ratio and generating contrast for cryo-EM images with convolutional neural networks. Palovcak E, Asarnow D, Campbell MG, Yu Z, Cheng Y. IUCrJ 7 1142-1150 (2020)
- Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation. Lainé A, Labiad O, Hernandez-Vargas H, This S, Sanlaville A, Léon S, Dalle S, Sheppard D, Travis MA, Paidassi H, Marie JC. Nat Commun 12 6228 (2021)
- TGFβ: Signaling Blockade for Cancer Immunotherapy. Chen SY, Mamai O, Akhurst RJ. Annu Rev Cancer Biol 6 123-146 (2022)
- 3DFlex: determining structure and motion of flexible proteins from cryo-EM. Punjani A, Fleet DJ. Nat Methods 20 860-870 (2023)
- A large expert-curated cryo-EM image dataset for machine learning protein particle picking. Dhakal A, Gyawali R, Wang L, Cheng J. Sci Data 10 392 (2023)
- A micellized bone morphogenetic protein-7 prodrug ameliorates liver fibrosis by suppressing transforming growth factor-β signaling. Cho K, Kim NH, Seo SH, Song SH, Jeong CH, Kim HS, Um JE, Ku M, Yang J, Park JY, Ahn SH, Yook JI, Kim SU. Am J Cancer Res 12 763-778 (2022)
- A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8. Le VQ, Zhao B, Ramesh S, Toohey C, DeCosta A, Mintseris J, Liu X, Gygi S, Springer TA. Proc Natl Acad Sci U S A 120 e2304874120 (2023)
- Anti-GARP Antibodies Inhibit Release of TGF-β by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro. Igney FH, Ebenhoch R, Schiele F, Nar H. Immunohorizons 7 200-212 (2023)
- CWHM-12, an Antagonist of Integrin-Mediated Transforming Growth Factor-Beta Activation Confers Protection During Early Mycobacterium tuberculosis Infection in Mice. Scott NR, Thirunavukkarasu S, Rangel-Moreno J, Griggs DW, Khader SA. J Interferon Cytokine Res 42 421-429 (2022)
- De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8. Roy A, Shi L, Chang A, Dong X, Fernandez A, Kraft JC, Li J, Le VQ, Winegar RV, Cherf GM, Slocum D, Poulson PD, Casper GE, Vallecillo-Zúniga ML, Valdoz JC, Miranda MC, Bai H, Kipnis Y, Olshefsky A, Priya T, Carter L, Ravichandran R, Chow CM, Johnson MR, Cheng S, Smith M, Overed-Sayer C, Finch DK, Lowe D, Bera AK, Matute-Bello G, Birkland TP, DiMaio F, Raghu G, Cochran JR, Stewart LJ, Campbell MG, Van Ry PM, Springer T, Baker D. Nat Commun 14 5660 (2023)
- Delineating Pixantrone Maleate's adroit activity against cervical cancer proteins through multitargeted docking-based MM\GBSA, QM-DFT and MD simulation. Almasoudi HH, Nahari MH, Alhazmi AYM, Almasabi SHA, Al-Mansour FSH, Hakami MA. PLoS One 18 e0295714 (2023)
- Discovery of a new class of integrin antibodies for fibrosis. Zhang J, Wang T, Saigal A, Johnson J, Morrisson J, Tabrizifard S, Hollingsworth SA, Eddins MJ, Mao W, O'Neill K, Garcia-Calvo M, Carballo-Jane E, Liu D, Ham T, Zhou Q, Dong W, Meng HW, Hicks J, Cai TQ, Akiyama T, Pinto S, Cheng AC, Greshock T, Marquis JC, Ren Z, Talukdar S, Shaheen HH, Handa M. Sci Rep 11 2118 (2021)
- Extracellular Vesicle-associated GARP/TGFβ:LAP Mediates "Infectious" Allo-tolerance. Burlingham WJ, Jankowska-Gan E, Fechner JH, Little CJ, Wang J, Hong S, Molla M, Sullivan JA, Foley DP. Transplant Direct 9 e1475 (2023)
- Family-wide analysis of integrin structures predicted by AlphaFold2. Zhang H, Zhu DS, Zhu J. Comput Struct Biotechnol J 21 4497-4507 (2023)
- Hyaluronan, Transforming Growth Factor β, and Extra Domain A-Fibronectin: A Fibrotic Triad. McKeown-Longo PJ, Higgins PJ. Adv Wound Care (New Rochelle) 10 137-152 (2021)
- Integrin β3 Induction Promotes Tubular Cell Senescence and Kidney Fibrosis. Li S, Jiang S, Zhang Q, Jin B, Lv D, Li W, Zhao M, Jiang C, Dai C, Liu Z. Front Cell Dev Biol 9 733831 (2021)
- Latency-associated Peptide Degradation Fragments Produced in Stellate Cells and Phagocytosed by Macrophages in Bile Duct-ligated Mouse Liver. Inoue I, Qin XY, Masaki T, Mezaki Y, Matsuura T, Kojima S, Furutani Y. J Histochem Cytochem 69 723-730 (2021)
- Macrophage TGF-β signaling is critical for wound healing with heterotopic ossification after trauma. Patel NK, Nunez JH, Sorkin M, Marini S, Pagani CA, Strong AL, Hwang CD, Li S, Padmanabhan KR, Kumar R, Bancroft AC, Greenstein JA, Nelson R, Rasheed HA, Livingston N, Vasquez K, Huber AK, Levi B. JCI Insight 7 e144925 (2022)
- Measurement of Cell Intrinsic TGF-β Activation Mediated by the Integrin αvβ8. Seed RI, Nishimura SL. Bio Protoc 12 e4385 (2022)
- PKC-ζ mediated reduction of the extracellular vesicles-associated TGF-β1 overcomes radiotherapy resistance in breast cancer. Zhang F, Zheng Z, Wang L, Zeng W, Wei W, Zhang C, Zhao Z, Liang W. Breast Cancer Res 25 38 (2023)
- Specificity of TGF-β1 signal designated by LRRC33 and integrin αVβ8. Duan Z, Lin X, Wang L, Zhen Q, Jiang Y, Chen C, Yang J, Lee CH, Qin Y, Li Y, Zhao B, Wang J, Zhang Z. Nat Commun 13 4988 (2022)
- The lncRNA-miRNA-integrin alpha V ceRNA network can affect the occurrence and prognosis of gastric cancer. Chen ZZ, Wang WP, Xue HM, Liang Y. Int J Clin Exp Pathol 15 388-402 (2022)
- The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development. De A, Morales JE, Chen Z, Sebastian S, McCarty JH. Development 149 dev200472 (2022)
- Unveiling the multitargeted repurposing potential of taxifolin (dihydroquercetin) in cervical cancer: an extensive MM\GBSA-based screening, and MD simulation study. Almasoudi HH, Hakami MA, Alhazmi AY, Makkawi M, Alasmari S, Alghamdi YS, Mashraqi MM. Med Oncol 40 218 (2023)